#168 Polygenic Risk Scores with Giordano Bottà

DNA Today: A Genetics Podcast

Enter a giveaway on our social media! Win free enrollment to a 3-hour course in the Allelica PRS clinical academy covering the research behind PRS to clinical applications. You can enter by looking for us on Twitter, LinkedIn, and Instagram. This has been posted at 9am on January 21st and will end on February 4th.

Our guest this week is Giordano Bottà, a biologist and bioinformatician, who is joining us to discuss polygenic risk scores.

Giordano earned a PhD in Public Health and he has extensive experience in analysis of large genomics dataset. During his career he has had the opportunity to work with some of the top genomics experts in the world at the University of Oxford, publishing in the journal Nature.

He is a co-founder and CEO of Allelica, which created a software to help clinical genetics labs to perform polygenic risk score analysis.

On This Episode We Discuss:

Defining polygenic risk scores (PRS)?

How PRSs are empowering the next generation of clinical genomics

Types of conditions that PRS can be calculated for

Who can benefit the most from PRSs

How Allelica is addressing the underrepresentation of people of Non-European descent in genetic studies with PRS

Using PRS to assess risk for heart disease and cancer

To learn more about Giordano, check him out on Twitter, LinkedIn and Instagram, and stay up to date with Allelica on Twitter and LinkedIn.

Stay tuned for the next new episode of DNA Today on January 28, 2022 where we’ll be discussing cytogenomics! New episodes are released on the first and third Friday of the month. In the meantime, you can binge over 165 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. All episodes in 2021 and 2022 are also recorded with video which you can watch on our YouTube channel.

See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNApodcast.com. Questions/inquiries can be sent to [e-mail].

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