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Ep. 41: “Autoimmunity and Cancer Immunotherapy” Featuring Dr. Vijay Kuchroo
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Guest:
Dr. Vijay Kuchroo is the Samuel L. Wasserstrom Professor of Neurology at Harvard Medical School. His major research interests include the role of co-stimulation in autoimmune diseases, as well as cell surface molecules and regulatory factors that regulate the induction of T cell tolerance and dysfunction. He talks about the conditions necessary to differentiate Th17 cells and their role in autoimmunity. He also discusses his group’s discovery of Tim-3, an inhibitor receptor on T cells which is now being exploited for cancer immunotherapy.
Featured Products and Resources:
- Resources for Your T Cell Therapy Research
- Read interviews where immunologists tell their stories, discuss their research, and voice their thoughts and opinions on current topics in immunology.
The Immunology Science Round Up
Disrupting Calcium Homeostasis – Researchers showed that inherited variants in ITPR3 alter physiologically relevant Ca2+ signaling responses, driving defects in immune responses.
Light Chain Coherence in Antibodies – Among naturally occurring antibodies that have adapted to particular antigens, those with similar heavy chains usually have similar light chains.
Anti-CTLA-4 Antibodies Reprogram the Tumor Microenvironment – Scientists used single-cell RNA sequencing to dissect the immune response to anti-CTLA-4 blockade.
An Intranasal Booster for Sarbecoviruses – Researchers used a SARS-CoV-2 intranasal spike booster to elicit mucosal immune memory within the respiratory tract.
Image courtesy of Dr. Vijay Kuchroo
90 tập
Fetch error
Hmmm there seems to be a problem fetching this series right now. Last successful fetch was on April 09, 2024 22:11 ()
What now? This series will be checked again in the next day. If you believe it should be working, please verify the publisher's feed link below is valid and includes actual episode links. You can contact support to request the feed be immediately fetched.
Manage episode 346484207 series 2895470
Guest:
Dr. Vijay Kuchroo is the Samuel L. Wasserstrom Professor of Neurology at Harvard Medical School. His major research interests include the role of co-stimulation in autoimmune diseases, as well as cell surface molecules and regulatory factors that regulate the induction of T cell tolerance and dysfunction. He talks about the conditions necessary to differentiate Th17 cells and their role in autoimmunity. He also discusses his group’s discovery of Tim-3, an inhibitor receptor on T cells which is now being exploited for cancer immunotherapy.
Featured Products and Resources:
- Resources for Your T Cell Therapy Research
- Read interviews where immunologists tell their stories, discuss their research, and voice their thoughts and opinions on current topics in immunology.
The Immunology Science Round Up
Disrupting Calcium Homeostasis – Researchers showed that inherited variants in ITPR3 alter physiologically relevant Ca2+ signaling responses, driving defects in immune responses.
Light Chain Coherence in Antibodies – Among naturally occurring antibodies that have adapted to particular antigens, those with similar heavy chains usually have similar light chains.
Anti-CTLA-4 Antibodies Reprogram the Tumor Microenvironment – Scientists used single-cell RNA sequencing to dissect the immune response to anti-CTLA-4 blockade.
An Intranasal Booster for Sarbecoviruses – Researchers used a SARS-CoV-2 intranasal spike booster to elicit mucosal immune memory within the respiratory tract.
Image courtesy of Dr. Vijay Kuchroo
90 tập
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