Guest: Dr. Mitchell Kronenberg is a Professor and President Emeritus at La Jolla Institute for Immunology. His lab studies how innate-like T cells adapt to different tissue environments. He talks about his work on MAIT cells and mucosal immunology, as well as his time leading the Institute. Featured Products and Resources: Check out the program for…

Guest: Dr. Scott Canna is an Associate Professor of Pediatrics (Rheumatology), and Attending Physician, Pediatric Rheumatology and Immune Dysregulation at the Children’s Hospital of Philadelphia. His group studies the mechanisms of immune dysregulation. He talks about auto- and hyperinflammatory diseases and the role of IL-18. He also discusses hem…

Guest: Dr. Neelika Malavige is the Head of Dengue Global Program and Scientific Affairs at the Drugs for Neglected Diseases Initiative and a Professor in the Department of Immunology and Molecular Medicine at the University of Sri Jayewardenepura. Her research focuses on dengue: its pathogenesis, vascular leak, immune correlates of protection, and …

Guest: Dr. James Allison is the Regental Professor and Chair of the Department of Immunology, Olga Keith Wiess Distinguished University Chair for Cancer Research, Director of the Parker Institute for Cancer Research, Executive Director of the Immunotherapy Platform, and Director of the James P. Allison Institute at MD Anderson Cancer Center. Dr. Al…

Guests: Dr. Akiko Iwasaki is the Sterling Professor of Immunobiology and Molecular, Cellular, and Developmental Biology at Yale University and President of the American Association of Immunologists. Francisco Gomez-Rivera is an Immunology Program Graduate Student Candidate at the University of Michigan, and Dr. Jason (Swinburne) Augustine is a reti…

Guest: Dr. Dionna Williams is an Acting Associate Professor in the Department of Pharmacology & Chemical Biology at Emory University. Their research focuses on the effects of HIV infection on the brain. She talks about how HIV affects immune cells in the brain and how this can lead to neuropsychiatric symptoms. They also discuss therapeutic approac…

Guests: Dr. Akiko Iwasaki is the Sterling Professor of Immunobiology and Molecular, Cellular, and Developmental Biology at Yale University and President of the American Association of Immunologists (AAI), and Dr. Aimee Bernard is an Assistant Professor of Immunology and Microbiology at the University of Colorado. Dr. Iwasaki has a very active prese…

In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies (IUIS), in Cape Town, South Africa. We spoke with delegates about their research and impressions of the meeting, including their reasons for attending and the most memorable research presented. They discuss their experien…

Guest: Dr. David Gibb is an Assistant Professor at Cedars-Sinai Medical Center. His lab investigates inflammatory mechanisms in patients with sickle cell disease and lupus, focusing on mechanisms regulating immune responses to red blood cell antigens following transfusion. Featured Products and Resources: IMMUNOLOGY2024 is happening May 3-7, 2024, …

In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies, in Cape Town, South Africa, and recorded daily episodes discussing highlights of the conference. Here is the final of five special episodes from the meeting, in which Brenda and Jason discuss sessions on integrins and eb…

In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies, in Cape Town, South Africa, and recorded daily episodes discussing highlights of the conference. Here is the fourth of five special episodes from the meeting, in which Brenda and Jason discuss sessions on the HIV/AIDS ep…

In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies, in Cape Town, South Africa, and recorded daily episodes discussing highlights of the conference. Here is the third of five special episodes from the meeting, in which Brenda and Jason discuss research on T cell exhaustio…

In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies, in Cape Town, South Africa, and recorded daily episodes discussing highlights of the conference. Here is the second of five special episodes from the meeting, in which Brenda and Jason discuss research on the microbiome,…

In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies, in Cape Town, South Africa, and recorded daily episodes discussing highlights of the conference. Here is the first of five special episodes from the meeting, in which Brenda and Jason discuss the opening ceremony of the …

Guest: Dr. Anjali Kusumbe is a Group Leader and Director of the Tissue Imaging Centre at Oxford University. Her lab studies vascular changes over time with the aim of treating diseases. She talks about light sheet microscopy techniques, the aging immune system, and finding lymphatic vessels in bone. Featured Products and Resources: IUIS 2023 is alm…

Guest: Dr. Sophia Liu is a Core Faculty Member and Early Independence Fellow at the Ragon Institute of Mass General, MIT, and Harvard. She enjoys creating new ways to measure temporally and spatially dynamic cell interactions and is particularly interested in studying T- and B-cell development. Her lab’s research focuses on immune cell interactions…

Guest: Dr. Siobhan Burns is a Professor of Translational Immunology at University College London. Her group studies the underlying molecular and cellular mechanisms that give rise to primary immunodeficiency disorders. She talks about how genetic mutations affect immune function, and what inborn errors of immunity can teach us about general immunol…

Guest: Dr. Peter Fecci is a Professor of Neurosurgery at Duke University and the Director of the Duke Center for Brain and Spine Metastasis. His research focuses on brain tumor immunology and immunotherapy, and T cell dysfunction in glioblastoma and other intracranial cancers. He talks about activating T cells to target brain tumors and his team’s …

Guest: Dr. Alice Long is an Associate Member and Principal Investigator at Benaroya Research Institute at Virginia Mason, where her lab focuses on discovering how tolerance is lost in human autoimmunity and how therapy can restore tolerance. Featured Products and Resources: Attend IUIS 2023, the world’s leading conference in the field of immunology…

Guest: Dr. Kristin Anderson is an Assistant Professor at the University of Virginia, where her lab focuses on engineering T cells to overcome immune suppression in the tumor microenvironment. She talks about how her cancer diagnosis changed her career focus, strategies for targeting ovarian cancer, and her transition from postdoc to professor. Feat…

Guest: Dr. Vinod Blachandran is an Attending Surgeon and Lab Head at Memorial Sloan Kettering Cancer Center. He talks about neoantigen vaccines for pancreatic cancer, what can be learned from a rare group of long-term survivors, and how surgeon-scientist mentors have influenced his career. Featured Products and Resources: Stay up-to-date with the l…

Guest: Dr. Greg Delgoffe is an Associate Professor at the University of Pittsburgh. His lab studies the intersection of metabolism and immunity in cancer. He talks about the metabolism of immune cells in cancer and the effects of nutrients in the tumor microenvironment. Featured Products and Resources: Register for IUIS 2023! Download a free wallch…

Guest: Dr. Daniel Streicker is a Professor of Viral Ecology at the University of Glasgow, where his lab investigates pathogen transmission between species. He talks about vampire bats as a reservoir for rabies and approaches to vaccination that could prevent transmission. Featured Products and Resources: Register for IUIS 2023 in Cape Town, South A…

Guest: Dr. Jamie Spangler is an Assistant Professor at Johns Hopkins. Her lab implements a unique structure-based engineering approach to elucidate the determinants of protein activity and inform drug development. She talks about designing cytokine mimetics and how engineered cytokines could be used as therapeutics. Featured Products and Resources:…

Guests: Dr. Laura Raff is Associate Director, Sales, Immunology and Dr. Ami Ashar-Patel is a Senior Account Manager, Immunology at STEMCELL Technologies. Dr. Raff has a PhD in Molecular Microbiology and Immunology from the University of Southern California and Dr. Ashar-Patel has a PhD in Biochemistry and Molecular Pharmacology from the University …

Guest: Dr. Alessandro Sette is a Center Head, Division Head, and Professor at the La Jolla Institute of Allergy and Immunology. His lab focuses on understanding the immune response, measuring immune activity, and developing disease intervention strategies against cancer, autoimmunity, allergy, and infectious diseases. He talks about bringing a biot…

In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists, in Washington, DC. We spoke with delegates about their research and impressions of the meeting, including their reasons for attending, what they were most looking forward to, and the most memorable research presented. Featured Products and Reso…

Guest: Dr. Bana Jabri is the Sarah and Harold Lincoln Thompson Professor in the Department of Medicine and the Research Director of the Celiac Disease Center at the University of Chicago. Her research focuses on innate and mucosal immunity, particularly in celiac disease, autoimmune disorders, and inflammatory bowel disease. She talks about the mec…

In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the final of five special episodes from the meeting. Brenda and Jason talk about sessions on mucosal immunity, emerging pathogens, and having …

In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the fourth of five special episodes from the meeting. Brenda and Jason talk about micelles for drug delivery and how helminth infection affect…

In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the third of five special episodes from the meeting. Highlights include Dr. Anthony Fauci’s talk on the COVID-19 pandemic response and Dr. Dou…

In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the second of five special episodes from the meeting. Brenda and Jason discuss sessions on peripheral neuroimmune interactions and tumor cellu…

In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the first of five special episodes from the meeting, in which Jason and Brenda summarize symposia on B and T-helper cells, and metabolic and g…

Guest: Dr. Prasanna Jagannathan is an Assistant Professor of Medicine in Infectious Diseases and of Microbiology and Immunology at Stanford University. His research focuses on the mechanisms of clinical immunity to malaria. He talks about how repeated exposure to malaria can lead to tolerance without symptoms, promising vaccines and treatments to p…

Guest: Dr. Joshua Brody is the Director of the Lymphoma Immunotherapy Program at the Tisch Cancer Institute at Mount Sinai. The Brody lab studies basic and applied tumor immunology for the development of cancer immunotherapies, particularly for lymphomas and melanomas. He talks about dendritic cells to improve oncolytic virus immunotherapy and in s…

Guest: Dr. Doug Green is the Peter C. Doherty Endowed Chair of Immunology at St. Jude Children’s Research Hospital. His research focuses on the central mechanisms of cell death, survival, and the immune response. He talks about what happens when cell death fails, the role of Myc, and setting up collaborations in science. Featured Products and Resou…

Guests: Dr. Miriam Merad is the President & Scientific Programme Committee Co-Chair of the International Union of Immunological Societies (IUIS) and Dr. Mark Davis is the Scientific Programme Committee Chair. They talk about what to expect at the 2023 IUIS Congress being held November 27 – December 2 in Cape Town, South Africa. They discuss hosting…

Guest: Dr. Clovis Palmer is an Assistant Professor at Tulane University. He talks about how HIV hijacks metabolic processes and the role of HIF-1α in HIV infection. He also discusses using non-human primates to study SARS-CoV-2 and other viruses. Featured Products and Resources: IMMUNOLOGY2023 is taking place in Washington, DC from May 11-15th! Dow…

Guests: Dr. Mark Davis is the President of the American Association of Immunologists, and Drs. Shruti Naik and Daniel Mucida are chairing Major Symposia at the upcoming IMMUNOLOGY2023 meeting in Washington, DC, May 11-15. They discuss what to expect at IMMUNOLOGY2023 and the highlights of this year’s program. Featured Products and Resources: Regist…

Guest: Dr. Hao Wu is the Asa and Patricia Springer Professor of Structural Biology at Harvard Medical School. Her lab focuses on the molecular and cellular mechanisms that govern the assembly, regulation, and therapeutic intervention of supramolecular complexes in innate immunity. She talks about cryo-electron microscopy and how her team used it to…

Guest: Dr. Caroline Sokol is a Principal Investigator at Massachusetts General Hospital and an Assistant Professor of Medicine at Harvard Medical School. Her lab studies the innate immune control of allergic disease. She talks about the role of sensory neurons and dendritic cells in allergic responses and insights into allergies from her son’s firs…

Guests: In this special episode, Brenda and Jason chat with Drs. Daylon James and Arun Sharma, the hosts of the Stem Cell Podcast. Recorded in-person and led by Dr. Nicole Quinn from STEMCELL Technologies, the four hosts discuss the impact that podcasting has had on their careers and how it can make science and scientists more accessible. They also…

Guest: Dr. Miriam Merad is a Professor of Cancer Immunology and Director of the Marc and Jennifer Lipschultz Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai. Her research focuses on dendritic cells and macrophages. She talks about tissue-resident macrophages in COVID-19 and cancer. She also discusses her new role as Pr…

Guest: Dr. Jie Sun is the Harrison Professor of Medicine at the University of Virginia. His lab studies respiratory immunology under homeostasis and disease conditions. He talks about how long COVID compares to other post-viral conditions, and his lab’s work investigating mucosal immunity from mRNA vaccines. Featured Products and Resources: Abstrac…

Guest: Dr. Arthur Liesz is a Professor of Experimental Neurology at the University of Munich. The Liesz lab is interested in the interplay between the brain and the immune system after stroke. He talks about the inflammatory response to stroke, including T cell-modulated microglial activation. He also talks about stroke aftermath, including T cells…

Guest: Dr. Vijay Kuchroo is the Samuel L. Wasserstrom Professor of Neurology at Harvard Medical School. His major research interests include the role of co-stimulation in autoimmune diseases, as well as cell surface molecules and regulatory factors that regulate the induction of T cell tolerance and dysfunction. He talks about the conditions necess…

Guests: Dr. Kristin Patrick is an Assistant Professor and Dr. Robert Watson is an Associate Professor at Texas A&M University. Their joint lab investigates innate immune regulation during bacterial infection. They talk about gasdermin D and cell death in tuberculosis, and how running a lab together helps them prioritize mentorship. Featured Product…

Guest: Dr. Henrique Borges da Silva is an Assistant Professor at the Mayo Clinic in Arizona. His main research focus is determining how extracellular nucleotides affect transcriptional, metabolic, and functional mechanisms of CD8+ T cells in response to viral infections and cancer. He talks about where extracellular ATP comes from, and how there co…

Guest: Dr. Indira Mysorekar is a Professor of Medicine and Chief of Basic and Translational Research at Baylor College of Medicine. Her lab studies host–microbial interactions in the urinary bladder and the placenta. She discusses the role of the microbiome and the aging immune landscape in recurrent urinary tract infections. She also talks about h…

Guest: Dr. Ruth Ley is Managing Director of the Max Planck Institute for Biology Tübingen and Director of the Department of Microbiome Science. Dr. Sara Clasen is a postdoctoral fellow in the same lab. Together, they’re interested in the co-evolution of humans with their microbiomes. They use basic science to investigate the evolutionary history of…