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1 #625: Creating an agile brand with composable approaches, featuring Chris Bach 47:35
Episode: 64 - Peyton Greenside on AI’s Role in Antibody Engineering, Optimization, and More
Manage episode 434000426 series 2967424
In this episode of The Chain, host Nimish Gera, Ph.D., vice president of biologics at Mythic Therapeutics, speaks with Peyton Greenside, CSO and co-founder of BigHat Biosciences, about the role of AI and machine learning in antibody engineering and targeting complex modalities, including bispecifics and ADCs. Greenside also discusses the work her organization does, what BigHat is doing to ensure the quality of data to train their AI models with, the methods of approaching harder targets such as GPCRs, and certain properties that AI can optimize better.
71 tập
Manage episode 434000426 series 2967424
In this episode of The Chain, host Nimish Gera, Ph.D., vice president of biologics at Mythic Therapeutics, speaks with Peyton Greenside, CSO and co-founder of BigHat Biosciences, about the role of AI and machine learning in antibody engineering and targeting complex modalities, including bispecifics and ADCs. Greenside also discusses the work her organization does, what BigHat is doing to ensure the quality of data to train their AI models with, the methods of approaching harder targets such as GPCRs, and certain properties that AI can optimize better.
71 tập
Tất cả các tập
×1 Episode: 68 - Changing the Game of Protein-Protein Interactions With Randolph Lopez 46:00
1 Episode: 67 - Anthony Tolcher Discusses Oncology, Dual-Payload Technology, and the ADC Field 42:34
1 Episode: 66 - John Lambert on Antibody Drug Conjugates Then, Now, & Beyond 39:43
1 Episode 65- Tariq Ghayur on the Renaissance of Bispecifics and ADCs, AI, and More 31:55
1 Episode: 64 - Peyton Greenside on AI’s Role in Antibody Engineering, Optimization, and More 32:31
1 Episode: 63 - Discussing Protein Signaling and Structural Biology With Andrew Kruse 38:18
1 Episode: 62 - AI/ML in Antibody Discovery and Engineering: Reality, Hope, Future, and Hype 1:03:57
1 Episode: 61 - Tomoyuki Igawa Discusses Leadership and His Experiences in Discovery and Development 55:04
1 Episode: 60 - Lesley Millar-Nicholson on Technology Licensing, Navigating Patents, and Building Teams 48:14
1 Episode: 59 - Gabriel Rocklin on Protein Biophysics and Protein Design 33:10
1 Episode: 58 - Janine Schuurman Reflects on the Key Lessons and Accomplishments of Her 20-Year Career 55:05
1 Episode: 57 - The Future of Bispecific Antibody Drug Conjugates With Rakesh Dixit, Ph. D. 33:06
1 Episode: 56 - Thomas Sakmar on the Golden Age for the Application of Biologics to GPCR Pharmacology 44:38
1 Episode: 55 - Tala Fakhouri Discusses AI/ML for Biologics Drug Discovery & Development 33:27
1 Episode: 54 - Enkelejda Miho on the Current State of AI: Drug Development, Research, and the Future 29:20
1 Episode: 53 - Jonathan Sockolosky on Breaking Into Biotech and Making Real Progress in Ovarian Cancer Treatments 26:48
1 Episode 52: Entrepreneurship in Immunotherapy: Capstan’s Adrian Bot on Teambuilding 23:31
1 Episode: 51 - Setting the Right Strategy to Drive Engineering Parameters for Solid Tumor-Targeting T Cell-Engagers 53:45
1 Episode: 50 - Pivoting Research with Antibody Drug Conjugates 31:20
1 Episode: 49 - Building a Next Generation Bioproduction Platform 23:30
1 Episode: 48 - A Conversation with Peter Tessier: Classifying Antibodies to Assess Biologics Developability Features Early in the Discovery Process 48:01
1 Episode: 47 - Bonus Episode with PEGS Young Scientist Keynote Dr. Andrew Anzalone on Engineering Prime Editor Proteins for Therapeutic Applications 40:43
1 Episode: 46 - Leveraging Albumin and IgG FcRn-Mediated Regulation in Therapeutic Development 36:20
1 Episode: 45 - Advances in Targeted Protein Degradation 30:16
1 Episode 44: Structure Forward: Using Structural Biology Pipelines to Achieve Favorable Antibody Responses 31:46
1 Episode: 43 - Evolution of Antibody Technologies 28:26
1 Episode: 42 - Machine Learning Informatics for Antibody Discovery 36:04
1 Episode: 41 - Introduction and Evolution of the Antibody Patent Landscape 20:30
1 Episode 40: Exploring Developability Concepts with Bispecific Antibodies 15:53
1 Episode 39: René Hoet on Antibody Discovery and Following Your Heart 20:29
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