Invent: Health. Each episode, we're joined by the top scientists, engineers, and academics working at the vanguard of this vital industry, to give you a behind-the-scenes look at the world of health.
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Invent: Life Sciences, is a podcast exploring the impact of biology and technology on the life sciences sector. Each week, we're joined by the top scientists, engineers, and academics working at the vanguard of this vital industry, to give you a behind-the-scenes look at the world of the life sciences.
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The Highlights: A look back at the best moments of Invent: Life Sciences Series 2
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Throughout this series of Invent, we have brought you cutting-edge developments in the Life Sciences industry. We have spoken to a wide range of guests who have provided fascinating insights into the manufacture of cell and gene therapies, and what developments in drug testing mean for the future of genetic research. A big thank you to all our gues…
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Process Analytics: how can analytics accelerate the development and manufacture of cell and gene therapies?
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Throughout this series, we’ve explored different diseases we target, the sorts of cells which are under development as therapies, and how the therapies themselves are manufactured. With all this innovation, we shouldn’t be surprised by the increased focus on the means by which processes and products themselves are characterised. So, do current proc…
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iPSCs: how could stem cells revolutionise the manufacture of advanced therapies?
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Across the life sciences industry, there is much excitement over the potential impact of stem cells in medicine. And it is clear why; these cells, which can be differentiated into any other cell type, could rewrite the playbook in terms of sourcing cellular material for advanced therapies manufacture. So how might therapy developers benefit from th…
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Sex and gender in medical research: how can a focus on the individual improve health outcomes for marginalised groups?
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Throughout almost all of medical history, it was assumed that the average white male response to drug trials could be extrapolated to all potential recipients. But when we look at the poorer health outcomes for women and minorities, could the underlying assumptions in medical research be a contributing factor? If so, what is being done to solve the…
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Organoids: how are in-vitro models revolutionising drug development and testing?
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Pharmaceutical companies undertake rigorous clinical trials in order to find out which drugs are safe. But in order to better protect the people volunteering for these tests, regulators decreed that data from studies on animals would be the primary evidence needed before approving a clinical trial in humans. Testing drugs on animals has many ethica…
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The Blood Brain Barrier: can innovations in delivery help us unlock the brain?
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Modern medicine has helped us develop many effective treatments for diseases found throughout the body, but we’ve yet to have the same success with the brain. The so-called 'blood brain barrier' controls the passage of molecules out of the blood and into the brain, and so it’s not as easy to use the bloodstream to carry therapeutic molecules as we …
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Small Molecules: can new classes of drug target reinvigorate drug discovery?
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In the pharmaceutical industry, there is a desire to go beyond the traditional ‘compound x acts on protein y,’ and achieve a more nuanced effect on the underlying biology. So, could innovative approaches to small molecules open up a wider application space? And what benefits might this bring to cash-strapped healthcare systems? To find out, join us…
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Cell and gene therapy: how can we transform artisan treatments into mass-market cures?
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Cell and gene therapies are extremely effective but their complex production processes, arduous supply chain, and life-critical logistics have prevented mass market adoption. Could digitisation and AI provide a breakthrough in manufacturing? Would more companies be willing to work together on standardisation to provide more flexibility? To find out…
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mRNA: What did Covid teach us about drug development and distribution?
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The Covid vaccination campaign demonstrated the effectiveness of mRNA-based treatments, so what else is this technology capable of? How can we improve our manufacturing and distribution to ensure treatments are available to those who need them most? To find out, join us on Invent: Life Sciences, a podcast brought to you by technology and product de…
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Introducing Invent: Life Science Series 2
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Invent: Life Sciences is back for Season 2! Invent: Life Sciences is a podcast about the future of life science and technology, hosted by Head of Cell Gene Therapy and Biotechnology at TTP, Stuart Lowe. Each episode, we’ll be joined by the top scientists, designers, business leaders, and academics working at the vanguard of this vital industry, to …
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Over the course of this season, one thing has kept coming up across all the episodes - the power of big data in health tech. From its uses in the current AI revolution, to universal health records and even in new sustainable practices, the way in which huge data sets are allowing health practitioners to create new products and services is as fascin…
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Rapid Innovation: Reducing Time from Idea to Impact
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Speed is not normally something you would associate with the highly regulated world of health tech. “Rapid” time frames tend to be in the space of 3-5 years. But the Covid panic changed this - the war footing it caused brought times down enormously. It’s something that TTP played a hand in as well with Covent, TTP’s rapid manufacture ventilator for…
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Cardiac Health: Prevention or Intervention?
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There’s a multitude of ways to treat Cardiac issues, and it’s about more than just health tech. While technologies that intervene after a cardiac event has taken place are coming on leaps and bounds - from ablation catheters to pacemakers - preventative measures are seen by many as the way forward. Whether it is improved sensing technologies, the r…
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Designing for Trust: How to Create Trust in Health Tech
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Trust in healthcare is one of the highest for any industry, but it’s a different story for the technology sector. People will inherently trust their doctor, but social media, or medical advice from the internet? Much less so. But as healthcare and technology become ever more entwined, how do those designing healthcare’s digital products ensure thos…
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Imaging Technologies: Smaller, Cheaper, Better?
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Medical imaging technologies have long been dominated by big, expensive machines that take up their own room within hospitals. The level of detail they can give is extensive and vital, and they are now even developing new fusion technologies that can combine nuclear, ultrasound, and MRI technologies together. But there is a new range of technologie…
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Sustainability is a word now ubiquitous in healthcare. But too often it is thought about with a short-sighted lens, promoting potentially superficial changes in micro areas over innovations that would reduce healthcare’s carbon footprint on a macro level. So how can we solve this? What could a new paradigm for discussing sustainability in healthcar…
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Calling all Invent: Life Sciences Subscribers! While you wait for more episodes, make sure to subscribe to our sister podcast, Invent: Health, which has just begun its second season. Listen to the trailer here now! Invent: Health sees host Matt Parker explore the fascinating future of Health technologies. From new closed-loop systems for diabetes t…
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Epilepsy: Understanding the brain when neurological disorders occur
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Neurological disorders have a really significant patient burden, with some estimates suggesting the impact as many as 1 billion people across the globe. But simultaneously, these are diseases which are both challenging to treat and still remain relatively poorly understood. Snapshots of the brain have been available through imaging technologies for…
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Diabetes Monitoring: Human out of the loop
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In this first episode of Invent:Health Season 2, Matt Parker speaks to Chris Dawson, Head of Biosensing at TTP, and Dr. Andrew Chapman, CEO, and Co-Founder of Carbometrics, to explore how patients can be taken out of this monitoring-delivery loop and what technologies are out there that can automate the process entirely. This Week's Guests Chris Da…
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Invent:Health from TTP - Season 2 Trailer
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Today we launching the trailer for the Invent Health podcast. Each week we're going to be joined by the top scientists, engineers, and academics working to give you a behind-the-scenes look at the world of health tech.Bởi invent@ttp.com (TTP plc)
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Behavioural Science: How to do what's good for us
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Doing what’s good for you should seem like second nature, so why is it that we as humans so often don’t do things which we know will be effective when it comes to our own health and wellbeing? From difficulties in quitting smoking to the 25% of prescriptions in the UK that are left unfilled, medical non-adherence has profound effects on the health …
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Mental Health: How to think about feeling
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There is now a widespread awareness of the gravity of mental health issues in the general public, and equally in the world of healthcare. But in tandem with its rise we've seen the growth of the so-called "wellness industry", which too often promotes pseudo scientific solutions to the most complex of problems. So how is the health tech industry res…
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Neurotech: what is it? Elon Musk’s brain implants that herald a dystopian sci fi future? Or life saving technology which will be able to cure a multitude of injuries: back pain, epilepsy, even paralysis. In this episode of Invent: Health, we take a look at the hype vs the reality in the thrilling field of neurotech, speaking to experts from TTP and…
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Of all the senses, sight is perhaps our most important. The eye is one of the most incredible organs in nature: it enables us to perceive the world around us, understanding our world through images. And yet we only see a small aspect of reality. But the eye is important beyond just sight. It can also provide a window into our overall health, showin…
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Sustainable Healthcare: How to take action
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Humans are designed to make decisions in the now, not ones in the abstract long term. That’s why ‘cathedral thinking’ comes so hard to us - so it's understandable that making healthcare more sustainable is hard when its primary function is first and foremost to save lives today, not the planet tomorrow. It's easy to say you want to be more sustaina…
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Surgical Robotics: How to build a robot
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Surgical robotics are all the rage right now. Attracting huge investment from the biggest names in healthcare devices, the use of robots in surgery has the potential to change the industry in some really profound and exciting ways. However, some have criticised their implementation as an unnecessary expense when humans can perform these tasks just …
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Healthcare's coming home: How to fit a hospital into your home
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Healthcare’s coming home, it’s coming home… Or is it? Recent years - and increasingly since COVID 19 - have seen healthcare moving into the home, with patients using more digital products to track their health from the comfort of their sofas. But why? What was the initial trigger for this? What are the risks and benefits? Will this see a dystopian …
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What is pain? Where does it start and end? In the mind, nerve endings, or somewhere else? In this final episode of the first season of Invent: Health from TTP, we’ll be exploring the many and varied facets of this most essential of human experiences. Speaking with specialists in the fields of psychology and neuroscience, we’ll find out what is bein…
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Invent: Health from TTP - Season 1 Trailer
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Hello and welcome to Invent: Health, a podcast from technology and product development company TTP. Invent: Health is a podcast about the future of health and technology, hosted by TTP Design and Strategy consultant, Matt Millington. Each week, we’ll be joined by the top scientists, designers, business leaders and academics working at the vanguard …
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Bonus - Eye health: The Invisible Pandemic
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We’re currently taking a short hiatus after our first season, where we covered everything from curing blindness to controlling pain; from making hospitals more sustainable to putting a hospital in your home. Before we come back with season two, our friends over at the Life Sciences team here at TTP are going to be dropping their very own series in …
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Life Science Investment: How to invest in change
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The pandemic drastically altered the landscape for investment flowing into the Life Sciences. Not only was there more money going in, but the market needs changed too, with an unprecedented focus on scaling sectors like testing and vaccines. But what did this mean for sectors which were not on the Covid front line? What happened to the trends that …
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Diagnostics: How to do self-testing better
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In the past decade, two events have sent shockwaves through the diagnostics industry: Theranos and Covid. The first, is a parable against faking it in an industry which rightly prizes accuracy and safety. The second was an almost insatiable demand for diagnostic testing kits, where the speed of information took second place to accuracy. Was Elizabe…
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Cell Therapy Manufacture: How to scale the manufacture of living drugs
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Following our first episode of two focusing on cell and gene therapies, outlining the promise and practicalities of delivering curative therapies for chronic diseases, we now focus on cell therapies - so called ‘living drugs’ that are both as powerful as they are complex. Despite the impressive trials and life-changing impacts at the individual lev…
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Cell and Gene: How to make advanced therapies accessible
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With therapies like cell and gene - amongst some of the most significant innovations in modern medicine - the idea of delivering cures for conditions from cancer to diabetes is now within the realm of scientific possibility. But will it be possible to provide the benefits of advanced therapies to all? Should we expect our healthcare systems to foot…
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Preclinical drug development: How to simulate the human body
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From cosmetics to medicines, animal testing is still widely mandated by regulators. Up to now, there have been few other ways to gather information about the potential human response to drug candidates. But are animal models still the most effective way to test drugs before we use them in humans? Or are these in vivo models outdated, ready to be re…
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The hunt to discover new pharmaceuticals in areas of high unmet need can be complex, time-consuming, and costly. For every life saving therapy that hits the market, thousands and even millions of candidate drugs are rejected. A new technology could be changing the way we home in on the most effective therapy: AI. The use of AI in drug discovery - w…
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Synthetic Biology: How to change your genes
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What is the potential of synthetic biology? A chance to create life-changing therapies by speaking cells’ very own language? Or could rogue researchers use it to turn our own biology against us? Since synthetic biology emerged as a field, the aspirations for its benefits have been as speculative as the concerns about its misuse, making one of the m…
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When the first human genome was sequenced, the whole project was estimated to have cost some 3 billion dollars and took over 13 years. Now, with massively parallel Next Generation Sequencing it is possible to sequence the human genome in less than 24 hours at a cost of under $1,000. With a rapid decline in sequencing costs, both the number of appli…
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Invent: Life Sciences from TTP - Trailer
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Following our thrilling first series of Invent all about health technology, the team at TTP are back with a new series all about the Life Sciences, to explore the impact of biology and technology on the life sciences sector. Life sciences are often referred to as the Fourth Industrial Revolution, deploying biology and technology in real-world appli…
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