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Authentic Biochemistry Podcast. Alzheimer’s Disease coda. Dr Daniel J Guerra.04sept24
Manage episode 438231971 series 3137613
Correction:
In my lecture I incorrectly used the W single letter designation as representing tyrosine. I miss-spoke.
W=tryptophan while Y=tyrosine.
The WW domain discussion is important for specific protein:protein interactions wherein the tryptophan (W) residues (found in the beta1 and beta 3 folds) are separated by 20 -22 amino acids that contain certain tyrosine (Y) residues in the beta2 region which may become phosphorylated thus generating phosophotyrosine binding (PTB)domains that are recognized by other proteins.
I apologize for the error.
References
Exp Biol Med (Maywood). 2015 Mar; 240(3):375–382
Cellular Physiology and Biochemistry (2017) 41 (3): 1189–1198.
PNAS 2022 Sep6;119(36):e2204069119
Alzheimer's Research & Therapy.2024.volume 16, Article number: 144 Joel, B. 1977. Vienna [Strangers;lp]
https://open.spotify.com/track/4U45aEWtQhrm8A5mxPaFZ7?si=240c0d811f164b7c
Beethoven, LV. 1816. Seventh Symphony A major. Op92.
https://open.spotify.com/album/2kDHEJxutXleLTNCctvgSB?si=qefvirqXSviiOqPmvWME7w
--- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
794 tập
Manage episode 438231971 series 3137613
Correction:
In my lecture I incorrectly used the W single letter designation as representing tyrosine. I miss-spoke.
W=tryptophan while Y=tyrosine.
The WW domain discussion is important for specific protein:protein interactions wherein the tryptophan (W) residues (found in the beta1 and beta 3 folds) are separated by 20 -22 amino acids that contain certain tyrosine (Y) residues in the beta2 region which may become phosphorylated thus generating phosophotyrosine binding (PTB)domains that are recognized by other proteins.
I apologize for the error.
References
Exp Biol Med (Maywood). 2015 Mar; 240(3):375–382
Cellular Physiology and Biochemistry (2017) 41 (3): 1189–1198.
PNAS 2022 Sep6;119(36):e2204069119
Alzheimer's Research & Therapy.2024.volume 16, Article number: 144 Joel, B. 1977. Vienna [Strangers;lp]
https://open.spotify.com/track/4U45aEWtQhrm8A5mxPaFZ7?si=240c0d811f164b7c
Beethoven, LV. 1816. Seventh Symphony A major. Op92.
https://open.spotify.com/album/2kDHEJxutXleLTNCctvgSB?si=qefvirqXSviiOqPmvWME7w
--- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
794 tập
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