Biopharma EHS Podcast Episode No. 17

Biopharma EHS

Containment Validation and Surrogate Monitoring

In this episode of the Biopharma EHS podcast, Dean M. Calhoun, CIH, President and CEO of Affygility Solutions discusses the following topics:

• A review of Episode no. 16 of the Biopharma EHS podcast. In that episode, Dean M. Calhoun, President and CEO of Affygility Solutions, and Dr. Joe Nieusma, Sr. Occupational Toxicologist with Affygility Solutions discuss Category 4 and 5 potent compounds. Our discussions include what factors determine a Category 4 or 5 potent compound, why the occupational exposure limit (OEL) alone is not enough to determine if a specific compound falls into a category 4 or 5 control band, and specific examples of potent compounds that are classified into these control bands.
• An interview with Matt Meiners, Division Manager, Laboratory Services for the Bureau Veritas, Lake Zurich, Industrial Hygiene Laboratory. In this interview, Dean and Matt discuss containment validation and surrogate monitoring. Often call SMEPAC testing. Matt provides insight into why containment validation is necessary, the advantages and disadvantages of different surrogate compounds, the sensitivity of their industrial hygiene laboratory methods for surrogate compounds, the advantages and disadvantages of the total dust versus the Institute of Occupational Medicine (IOM) method of sampling.
• Upcoming events and happenings of interest to environmental, health and safety professionals in the biotechnology, pharmaceutical, and medical device industries. These events include:
• Affygility Solutions' webinars. These webinars include:
1. Advance Topics in Potent Compound Safety
2. Dermal Exposure and Absorption of Active Pharmaceutical Ingredients
3. Isoflurane Safety
• Society of Toxicology Annual Meeting in San Francisco, CA
• Society of Chemical Hazard Communication Spring Meeting in Nashville, TN
• The above webinars are a great way for environmental, health and safety professionals to obtain certification maintenance points.

If you have questions regarding this podcast, please email podcast @ affygility.com