8. Let’s Read A Paper Written By Nobel Prize Laureates, 2023: Part 2 (mini-series: Reading-2) Foundational Skills In Life Sciences podcast

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Threshold is a Peabody Award-winning documentary podcast about our place in the natural world. Each season, we take listeners on a journey into the heart of a complex environmental story, asking how we got here and where we might be headed. In our latest season, Hark, we hand the mic over to our planet-mates and investigate what it means to truly listen to nonhuman voices—and the cost if we don't. With mounting social and ecological crises, what happens when we tune into the life all around us? Threshold is nonprofit, listener-supported, and independently produced.

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8. Let’s read a paper written by Nobel Prize Laureates, 2023: Part 2 (mini-series: reading-2)

cách đây khoảng một năm trước 24:44

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Nội dung được cung cấp bởi Dr. Synaptologica. Tất cả nội dung podcast bao gồm các tập, đồ họa và mô tả podcast đều được Dr. Synaptologica hoặc đối tác nền tảng podcast của họ tải lên và cung cấp trực tiếp. Nếu bạn cho rằng ai đó đang sử dụng tác phẩm có bản quyền của bạn mà không có sự cho phép của bạn, bạn có thể làm theo quy trình được nêu ở đây https://vi.player.fm/legal.

Let's enjoy the Nobel Prize announcement. How do we enjoy it? We will read one paper written by the Nobel Laureates, and dive deep. This episode is Part 2 of a multi-episode mini-series on reading. We will talk about: 1) how the Nobel Prize laureates are selected, 2) what a milestone article is, 3) why we would want to read the milestone article by the Nobel Laureates, and 4) who will benefit from this reading activity.
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#Science #Biology #Dr. Synaptologica #Podcasting Education #A Miniseries

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8. Let’s read a paper written by Nobel Prize Laureates, 2023: Part 2 (mini-series: reading-2)

Foundational Skills in Life Sciences

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Nội dung được cung cấp bởi Dr. Synaptologica. Tất cả nội dung podcast bao gồm các tập, đồ họa và mô tả podcast đều được Dr. Synaptologica hoặc đối tác nền tảng podcast của họ tải lên và cung cấp trực tiếp. Nếu bạn cho rằng ai đó đang sử dụng tác phẩm có bản quyền của bạn mà không có sự cho phép của bạn, bạn có thể làm theo quy trình được nêu ở đây https://vi.player.fm/legal.

Let's enjoy the Nobel Prize announcement. How do we enjoy it? We will read one paper written by the Nobel Laureates, and dive deep. This episode is Part 2 of a multi-episode mini-series on reading. We will talk about: 1) how the Nobel Prize laureates are selected, 2) what a milestone article is, 3) why we would want to read the milestone article by the Nobel Laureates, and 4) who will benefit from this reading activity.
(My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)

… continue reading

50 tập

#Science #Biology #Dr. Synaptologica #Podcasting Education #A Miniseries

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50. Happy 50th episode! 5:39

cách đây 11 ngày trước5:39

5:39

We have reached 50 episodes! Thank you for listening. Today, we will briefly talk about how I have kept sustainable podcasting so far. The most important thing may be that I have set my goal simple and single: It is to create high-quality content for you. That’s it. Here are links to two sources of podcast statistics that I mentioned in the episode. https://www.amplifimedia.com/blogstein-1/lyspqop3ylro9a2t7y2de820uwkgwx https://podcastindex.org/stats (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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49. Another well-crafted logic loop in Abstract by Nobel Laureates (mini-series: reading-30) 18:26

cách đây 18 ngày trước18:26

18:26

We will talk about the second of the two, well-crafted loops of logic, in the Abstract of a paper written by the Nobel Prize Laureates. Not all abstracts have this second loop. But when it is present, it gives a better overview of the impact of the presented work. We can find one of the best examples in our Abstract. We are reading the paper written by the Laureates, Dr. Katalin Karikó & Dr. Drew Weissman, that led to the Nobel Prize in Physiology or Medicine 2023. We call it the Milestone Article 1. Here are two sets of links related to the paper. Milestone Article 1: “Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA” by Karikó, Buckstein, Ni & Weissman. Immunity, 23(2): 165-75, 2005. DOI: https://doi.org/10.1016/j.immuni.2005.06.008 PDF: https://www.cell.com/immunity/pdf/S1074-7613(05)00211-6.pdf PubMed: https://pubmed.ncbi.nlm.nih.gov/16111635/ Copyright of the paper (as of March, 2025): See the pull-down menu “Article Info” near the top of the article webpage (Use the DOI above to reach it). Check the “User License” section which lists the “Elsevier user license”: --- http://www.elsevier.com/open-access/userlicense/1.0/ --- https://www.elsevier.com/about/policies-and-standards/open-access-licenses/elsevier-user For finding our Milestone Articles 1, 2 and 3 (i.e., three papers written by the Laureates that led to the Nobel Prize), visit the following website that shows the “Press Release” of the Nobel Prize in Physiology or Medicine 2023. Look for "Key publications" section. https://www.nobelprize.org/prizes/medicine/2023/press-release/ We discussed how to find Milestone Articles 1~3 as above, in Episode #10. Here is the link to the episode: https://synaptologica.buzzsprout.com/2219599/episodes/14122755 (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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48. Well-crafted logic loop in Abstract by Nobel Laureates (mini-series: reading-29) 19:32

cách đây 26 ngày trước19:32

19:32

I can visualize two well-crafted loops of logic, in the Abstract of a paper written by the Nobel Prize Laureates. Can you? We will talk about one of them in today’s episode. Such a loop, together with a linear progression, highlights the authors’ clear and logical thought process. We are reading the paper written by the Laureates, Dr. Katalin Karikó & Dr. Drew Weissman, that led to the Nobel Prize in Physiology or Medicine 2023. We call it the Milestone Article 1. Here are two sets of links related to the paper. Milestone Article 1: “Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA” by Karikó, Buckstein, Ni & Weissman. Immunity, 23(2): 165-75, 2005. DOI: https://doi.org/10.1016/j.immuni.2005.06.008 PDF: https://www.cell.com/immunity/pdf/S1074-7613(05)00211-6.pdf PubMed: https://pubmed.ncbi.nlm.nih.gov/16111635/ Copyright of the paper (as of March, 2025): See the pull-down menu “Article Info” near the top of the article webpage (Use the DOI above to reach it). Check the “User License” section which lists the “Elsevier user license”: --- http://www.elsevier.com/open-access/userlicense/1.0/ --- https://www.elsevier.com/about/policies-and-standards/open-access-licenses/elsevier-user (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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47. Why is the 2nd sentence important in an abstract? (mini-series: reading-28) 20:32

cách đây 5 weeks trước20:32

20:32

Let's analyze a single sentence in the Abstract of an impressive paper. It is the paper that led to the 2023 Nobel Prize in Physiology or Medicine. This is the paper that we call the milestone article 1 (Please see below for details). We will analyze the second sentence. Why is this sentence important? We will discuss four of my approaches to see that this sentence is important, beautiful and helpful for readers outside the field. It is fun to spend one episode for just a single sentence, and think deep about how it reveals the authors' logic. Here are two sets of links related to the paper written by the Laureates, Dr. Katalin Karikó & Dr. Drew Weissman of the Nobel Prize in Physiology or Medicine 2023. Milestone Article 1: “Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA” by Karikó, Buckstein, Ni & Weissman. Immunity, 23(2): 165-75, 2005. DOI: https://doi.org/10.1016/j.immuni.2005.06.008 PDF: https://www.cell.com/immunity/pdf/S1074-7613(05)00211-6.pdf PubMed: https://pubmed.ncbi.nlm.nih.gov/16111635/ Copyright of the paper (as of March, 2025): See the pull-down menu “Article Info” near the top of the article webpage (Use the DOI above to reach it). Check the “User License” section which lists the “Elsevier user license”: --- http://www.elsevier.com/open-access/userlicense/1.0/ --- https://www.elsevier.com/about/policies-and-standards/open-access-licenses/elsevier-user (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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46. Let’s analyze the Abstract of a paper written by Nobel Laureates (mini-series: reading-27) 27:59

cách đây 6 weeks trước27:59

27:59

Today, we will analyze the Abstract of an impressive paper. It is the paper that led to the 2023 Nobel Prize in Physiology or Medicine. This is the paper that we call the milestone article 1. We will have two essential pre-analysis sub-steps, and then we will analyze each sentence. During this analysis, we will read each sentence of the Abstract, examine the role of each sentence, and assign each sentence to a structural component, so that we will be able to understand the authors’ intention for each sentence. Here are two sets of links mentioned in this episode. All are related to the Laureates, Dr. Katalin Karikó & Dr. Drew Weissman of the Nobel Prize in Physiology or Medicine 2023. Milestone Article 1: “Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA” by Karikó, Buckstein, Ni & Weissman. Immunity, 23(2): 165-75, 2005. DOI: https://doi.org/10.1016/j.immuni.2005.06.008 PDF: https://www.cell.com/immunity/pdf/S1074-7613(05)00211-6.pdf PubMed: https://pubmed.ncbi.nlm.nih.gov/16111635/ Copyright of the paper (as of March, 2025): See the pull-down menu “Article Info” near the top of the article webpage (Use the DOI above to reach it). Check the “User License” section which lists the “Elsevier user license”: --- http://www.elsevier.com/open-access/userlicense/1.0/ --- https://www.elsevier.com/about/policies-and-standards/open-access-licenses/elsevier-user (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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45. Let’s read the Abstract of a paper written by Nobel Laureates (mini-series: reading-26) 20:34

cách đây 9 weeks trước20:34

20:34

Today, we will take a significant step towards understanding the 2023 Nobel Prize in Physiology or Medicine. We will read the Abstract of the Laureates’ most important paper that led to the Nobel Prize. This is the paper that we call the milestone article 1. We will have two essential pre-reading sub-steps, and then we will conduct the initial readings. These sub-steps will set the stage for a more in-depth exploration in the next episode. Here are two sets of links mentioned in this episode. All are related to the Laureates, Dr. Katalin Karikó & Dr. Drew Weissman of the Nobel Prize in Physiology or Medicine 2023. YouTube video of Nobel announcement (starting at ~2 minutes and 20 seconds) Embedded in Nobel website: https://www.nobelprize.org/prizes/medicine/2023/prize-announcement/ Standalone with time stamp: https://www.youtube.com/watch?v=0JP-yDsLc3k&t=2m20s Milestone Article 1: Immunity, 2005 DOI: https://doi.org/10.1016/j.immuni.2005.06.008 PDF: https://www.cell.com/immunity/pdf/S1074-7613(05)00211-6.pdf PubMed: https://pubmed.ncbi.nlm.nih.gov/16111635/ (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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44. An evolving reader: my phases through reading textbooks (Q&A-5: textbooks, part 2) 22:12

cách đây 11 weeks trước22:12

22:12

How are you reading life-science textbooks? My approach to reading textbooks has evolved significantly throughout my academic career, from student to researcher to instructor to course director. Today’s episode is part 2. We will discuss the last two phases of my experience. I am now in the fourth phase. I fully appreciate how well the authors summarized a vast amount of knowledge in one field of life sciences, in coherent and consistent manners. Please enjoy listening to my different phases of reading textbooks. It will be great if these episodes serve in stimulating your thoughts about how to read textbooks. (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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43. An evolving reader: my phases through reading textbooks (Q&A-5: textbooks, part 1) 22:13

cách đây 14 weeks trước22:13

22:13

How are you reading life-science textbooks? My approach to reading textbooks has evolved significantly throughout my academic career, from student to researcher to instructor to course director. Today’s episode is part 1. We will discuss the first two phases of my experience. My overall goal of the two-part episodes is to highlight the unique roles that textbooks play, different from those of primary research papers. Knowing these different purposes will help us read textbooks more effectively. (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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42. Happy Holidays! 1:01

cách đây 16 weeks trước1:01

1:01

Happy Holidays to you, and I wish you the very best in 2025!

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41. Exclude or include seemingly irrelevant experiences in your academic CV? (Q&A-4: CV) 22:01

cách đây 20 weeks trước22:01

22:01

“Should I exclude irrelevant experiences from my academic CV?” This is a question that students often ask. In this episode, I would like to give you my thoughts about this question. In general, there is a way of creating a comprehensive CV: it will show that you have unique experiences, and you are a careful and a thoughtful writer. The key would be for you to be proud of what you did in the past. I hope that this discussion will be useful for you. (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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40. Short or long CV for applying for a research position? (Q&A-3: CV) 16:23

cách đây 24 weeks trước16:23

16:23

“Should my CV be short or long, when I apply for a research assistant position in a college/university lab?” This is a question that students often ask. In this episode, I would like to give you my thoughts about this question. The content in a CV depends on the person’s career stage. But I have one common viewpoint for CVs at all stages. I would like to view the descriptions in the CV, during and after the undergraduate education, as the defining statements of the person. My thoughts about today’s question will be related to this viewpoint. At the same time, I agree that different professors and different students may have opinions different from mine. Let’s discuss them and share diverse perspectives, so that our thoughts will become deeper. (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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39. Eight key components define the Abstract structure (mini-series: reading-25) 18:57

cách đây 25 weeks trước18:57

18:57

How do top-tier scientific journals, like Nature, make sure their abstracts are clear and impactful? In today’s episode, we will identify the eight key components that make those abstracts effective, by naming the components in our own words, and clarifying their roles and order. Our system was inspired by the Nature document for the Abstract guidelines that we discussed in the Episode #38. Here is the URL that brings you directly to the Nature document: https://www.nature.com/documents/nature-summary-paragraph.pdf (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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38. The journal, Nature, dissects the Abstract structure (mini-series: reading-24) 13:26

cách đây 26 weeks trước13:26

13:26

What is the best way to learn how to read the Abstract of a scientific paper? In my view, the best way is to learn how the Abstract is structured in any paper. Today, we will learn it, by reading a very short document. It is a one-page document that describes the Abstract guidelines, provided by the journal, Nature. Here is the URL that brings you directly to the Nature document: https://www.nature.com/documents/nature-summary-paragraph.pdf Here is the URL of the webpage for the Instructions for Authors by Nature. The above document can be found as the hyperlink to the note, “annotated example” in the “Articles” section: https://www.nature.com/nature/for-authors/formatting-guide Here are the links to the Milestone Article 1 (Immunity, 2005) by the Laureates, Dr. Katalin Karikó & Dr. Drew Weissman of the Nobel Prize in Physiology or Medicine 2023. DOI: https://doi.org/10.1016/j.immuni.2005.06.008 PDF: https://www.cell.com/immunity/pdf/S1074-7613(05)00211-6.pdf PubMed: https://pubmed.ncbi.nlm.nih.gov/16111635/ (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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37. Announcement of The Nobel Prize in Chemistry 2024, relevant to life scientists! 9:23

cách đây 27 weeks trước9:23

9:23

The 2024 Nobel Prize was announced! Two days ago, it was in Physiology or Medicine. Yesterday, it was in Physics. Today, it was in Chemistry. The Nobel Prize in Chemistry was awarded to Dr. David Baker “for computational protein design”, and to Dr. Demis Hassabis and Dr. John Jumper, “for protein structure prediction.” Their work is directly related to life sciences. Let’s learn about the work by watching a YouTube video. It is the archived video of the announcement of The Nobel Prize. I am sure you enjoy listening to podcasts. I am also happy to report to you that Dr. David Baker launched “The Baker Lab Podcast” just two weeks before this recording! Here is the URL of the YouTube video: https://www.youtube.com/watch?v=bPjB9NRu8Jc Here is the URL of the same video, but with a timestamp at the start of slide presentation: https://www.youtube.com/watch?v=bPjB9NRu8Jc&t=4m40s Here is the URL of the same video, but embedded on the Nobel Prize website: https://www.nobelprize.org/prizes/chemistry/2024/prize-announcement/ Here is the URL of a new podcast, “The Baker Lab Podcast” hosted by Dr. David Baker: https://www.bakerlab.org/podcast/ Enjoy the video and the podcast! (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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36. Announcement of The Nobel Prize in Physics 2024, relevant to life scientists! 8:25

cách đây 27 weeks trước8:25

8:25

The 2024 Nobel Prize was announced! Yesterday, it was in Physiology or Medicine. Today it was in Physics. It was awarded to Dr. John Hopfield, and Dr. Geoffrey Hinton, “for foundational discoveries and inventions that enable machine learning with artificial neural networks.” It is somewhat (indirectly) related to my field, neuroscience! Let’s learn about the work by watching a YouTube video. It is the archived video of the announcement of The Nobel Prize. Here is the URL of the YouTube video: https://www.youtube.com/watch?v=SBGG4WNweEc Here is the URL of the same video, but embedded on the Nobel Prize website: https://www.nobelprize.org/prizes/physics/2024/prize-announcement/ Enjoy the video! (My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)…

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