34. Trailblazing Approaches to Sarcoma Treatment

Lab Rat Chat

Lab Rat Chat - Episode 34 with Dr. Ben Wylie

Get ready to embark on a fascinating scientific journey with our esteemed guest, Dr. Ben Wylie. We know you're curious about his career journey, his cutting-edge work in sarcoma research, and his innovative approach towards cancer treatment. So, we promise you an enlightening conversation that is sure to feed your curiosity and inspire your scientific spirit.
In the first part of our conversation, Dr. Wylie takes us through his journey, from his childhood fascination with the natural world to his current role in cancer research at the Telethon Kids Institute. He opens up about his career transitions, his love for academic research, and the critical work his team is doing in pediatric sarcoma to utilize a biodegradable material to deliver immunotherapy during surgery. This approach, which targets invisible micrometastatic disease left behind during surgery, could potentially transform the landscape of post-surgical cancer treatment.
The conversation takes an exciting turn towards veterinary research and the canine clinical trials to test the efficacy of their immunotherapy gel in dogs diagnosed with sarcoma. We discuss what hopes to be very promising results from this trial and how it can hopefully be translated into the human world. Stay tuned, and prepare for a thought-provoking ride into the world of scientific innovation.
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Resources & Links:

• A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence - PubMed (nih.gov)
• Sarcoma Translational Research | Telethon Kids Institute
• World-first clinical trial in Perth could lead to breakthrough treatment for children with sarcoma - ABC News

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Chương

1. 34. Trailblazing Approaches to Sarcoma Treatment (00:00:00)

2. Sarcoma Research and Career Journey (00:00:05)

3. Developing Immunotherapy Delivery for Cancer Surgery (00:11:46)

4. Advancing Cancer Treatment Through Veterinary Research (00:19:58)

5. Delivering Therapies in Surgery and Research (00:28:05)