Behind the MoonArk: How a Team of Artists Embraced Science to Send a Time Capsule to the Moon

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Hark | 8 | The Queen's English 30:00

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Living together in a group is a strategy many animals use to survive and thrive. And a big part of what makes that living situation successful is listening. In this episode, we explore the collaborative world of the naked mole-rat. Threshold is nonprofit, listener-supported, and independently produced. You can support Threshold by donating today . To stay connected, sign up for our newsletter . Operation frog sound! Send us your frog sounds for an upcoming episode. We want you to go out, listen for frogs and toads, and record them. Just find someone croaking, and hit record on your phone. It doesn’t matter if there’s background noise. It doesn’t even matter if you’re not sure whether or not you’re hearing an amphibian—if you think you are, we would love to get a recording from you. Please also say your name and where you are in the world, and then email the recording to us at outreach@thresholdpodcast.org…

cách đây 3 năm trước 20:57

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⚡ The MoonArk is both conceptual art and a time capsule. Almost 15 years ago, the idea was to create a time capsule carrying fragments of the world as we know it today and send it to the moon to be discovered in the distant future. Today, the project has 60 members from 18 institutions and over 250 contributing designers, scientists, poets, musicians etc. Mark Baskinger, one of the first to get involved with the project, shares what it was like at the beginning. ''The MoonArk was a conceptual idea concocted by a few pioneering faculty members here, namely, Red Whitaker in the Robotics Institute and Lowry Burgess, former Dean of the College of Fine Arts. And their thought was that if Carnegie Mellon were to go to the moon, it can't just be the sciences and the technologies and that side of campus represented and that the arts would surely have something to contribute.''

⚡ Working on MoonArk was creative and exciting but challenging. As our guests say, creating an object like the MoonArk goes beyond making it look nice. It has to be safe and resilient to different conditions. ''We wanted it to be beautiful and aesthetic. So we went about making it with no real knowledge of what it was going to take to get it there. So, when it was time to put the rubber on the road, we were like, 'Oh, my goodness. It has to go through all this different, rigorous testing,''' says Dylan.

⚡ Many components are handmade. What makes the MoonArk astonishing is the amount of work, especially manual work, that’s been put into its creation. ''[...], a sculptor metal worker made quite a contribution to this project. It was amazing to visit and watch him do this under the monitor, zoomed in significantly — getting to see the intricacy of the work that was a part of it. But the biggest issue was whether those micro welds would be strong and consistent enough to be able to sustain the rigorous trip that the MoonArk was going to go through,'' explains Matt.

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#Science #Natural Sciences #Social Sciences #Thermo Fisher #Interviews #Lab Research #Medical #Medical Science #Medicine #Nalgene #Research #Scientific Research

Science with a Twist

Behind the MoonArk: How a Team of Artists Embraced Science to Send a Time Capsule to the Moon

Science with a Twist

published cách đây 3 năm trước

Chia sẻ

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#Science #Natural Sciences #Social Sciences #Thermo Fisher #Interviews #Lab Research #Medical #Medical Science #Medicine #Nalgene #Research #Scientific Research

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Science with a Twist

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Science with a Twist

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Science with a Twist

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Science with a Twist

1
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⚡ What are the ramifications from a clinical research perspective if diversity is not appropriately represented in a clinical study populations? Even as diversity becomes increasingly important across different sectors, minorities continue to be left out of clinical trials and medical research studies. So, why is diversity so critical in clinical trials? Nik explains, "I think in terms of the ramifications if diversity is not appropriately represented — I think we, unfortunately, saw this clearly playing out during the pandemic when we were seeing a lot of the data emerging that many underrepresented patients, particularly black and Hispanic patients, were having worse outcomes with COVID. Yet when we were looking at a lot of the trials for vaccines and therapeutics, those patients were not being included in the studies. And then as a result, from a scientific standpoint, when the results of the studies came out, people were understandably questioning, ‘Are these results that we're seeing generalizable to all the patients with the disease and especially the patients who're having the worst outcomes?’" ⚡ Recruiting and enrolling more representative populations does not mean delaying the study. Despite what many people think, enrolling diverse populations in clinical trials won't slow down the process. Nik shares his experience with including underrepresented minorities in peri- and post-approval studies through decentralized clinical trial models. He says, "The great thing was that not only did we complete that study and we had the data and that really gave us a lot more confidence in our medicine but also that trial recruited in record time, which was one of the myths that people had been saying, 'Oh, we could have a more diverse trial population, but it's going to slow the study, and we don't want to do that.' So, this study, we had 84% from underrepresented populations and actually was one of the fastest studies that Genentech ever enrolled and was published in the New England Journal of Medicine." ⚡ Clinical trials must strive to be more diverse. Enhancing diversity in clinical trials is a win-win for the entire public health system, not just for underrepresented populations. Nik explains, "We're thinking about this very carefully at Genentech, and we're trying to make sure that our efforts in terms of improving diversity in clinical trials is not just a one-off thing, that we really make this part of just the routine way that we do every clinical trial." He adds, "I think our vision, as I mentioned, is that we really need to make enrolling a diverse and representative population a routine part of how we conduct all of our trials, which will not only increase the robustness of our research, but it will also help ensure broad patient access, and as we've seen from a few studies, not only will it not slow down studies but if done right can even accelerate trials. If we can do all of that, that can really represent a true win-win for patients, for us as a company, and for society as a whole."…

Science with a Twist

1
Putting Patients First: The Benefits of Decentralized Clinical Trials 26:05

cách đây 2 years trước26:05

26:05

⚡ Decentralized clinical trials aim to reduce patient burden. Decentralized clinical trials can help make research more patient-centric. Tim explains the role of decentralization, "It's fair to say that that change management component is absolutely critical in terms of the decentralized adoption, and I think, when I look ahead in terms of decentralization, I see an amazing landscape for patients and the partnerships with EmVenio and also the kind of opportunities Thermo Fisher Scientific has in really driving forward unique and collaborative solutions for the better of the patient and really focusing on reducing that patient burden." ⚡ We need to make clinical trials more patient-centric. Patient-centricity is key when it comes to improving participation in clinical trials and clinical research progress overall. Tim says, "As an industry, we talk about patient-centricity and I think we embrace significant patient-centricity by taking a research site with all the research professionals on board to the patient's home." ⚡ Representation in clinical trials matters. Diversity is vital to preventing and treating diseases across race and gender. Thad says, "A couple of stats recently — there was one study we supported where of the 2,500 patients that EmVenio enrolled, 65% were from underrepresented populations, and so it really showed that value there. And what we're seeing more broadly is that across the studies we support, greater than 40% of the patients we're working with come from minority populations. And so, to contrast that against industry stats of around 10% to 20% as an average, we're offering more than double the ability to reach these populations that otherwise don't have access. So I think what we're seeing is that the results are really bearing on the value that we're bringing together."…

Science with a Twist

1
No One Missed: Empowering Lung Cancer Patients with Biomarker Insights 29:03

cách đây 2 years trước29:03

29:03

⚡ There's a diversity mismatch in the oncology workforce. One of the biggest challenges in the oncology space is a lack of diversity in the workforce. The population of the United States is very diverse, while the oncology field is not. Dr. Upal Basu Roy says, "We know that the United States is very diverse. As we speak, the population is very diverse, and we have about 12% African Americans in the population — about 18% who identify as Hispanic/Latinx — and 3% of the population who identify as American Indians and Alaska natives. But is that diversity reflected in the oncology workforce? Absolutely not. So we have a problem. So if you look at the latest statistics from the ASCO workforce report in 2020, only 5% of oncologists identify as Hispanic/Latinx, 3% as Black or African American, and 0.1% as American Indian and Alaska native. So we have this mismatch." ⚡ Patients have better health outcomes when treated by doctors who look like them. Dr. Upal Basu Roy explains, "The population is very diverse, but the workforce is not diverse. So keeping that in mind, we created the Health Equity and Inclusiveness Research Awards specifically to foster minority scientists. Now you can ask me, ‘Why is that important?’ It is fundamentally important to have clinicians who look like patients because there's very good research that's shown that patients have better outcomes when they're treated by doctors who look like them. And patients are way more inclined to participate in clinical trials when those trials are being offered to them by clinicians who look like them." ⚡ ‘ No One Missed’ is an inclusive lung cancer campaign. ‘No One Missed’ is a community-led campaign driven by the LUNGevity Foundation. Dr. Upal Basu Roy talks about the campaign's main goals. He says, "As a scientist, I focus on science and innovation. But as a patient advocate, I focus on access. Because I think we need to keep in mind that science is a public good. Innovation is a public good. And we, as a patient advocacy group, need to make sure that the science we fund today reaches patients tomorrow. And biomarker testing targeted therapies are a huge piece of the treatment arsenal of lung cancer, and we, as a foundation, are committed to making sure that these innovative approaches treat patients no matter where they're diagnosed, no matter their gender, sexual orientation, their race and ethnicity, where they live, or their socioeconomic status."…

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Science with a Twist « » Behind the MoonArk: How a Team of Artists Embraced Science to Send a Time Capsule to the Moon

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Behind the MoonArk: How a Team of Artists Embraced Science to Send a Time Capsule to the Moon