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Welcome to LIVE WELL BE WELL, a podcast that challenges the way you think about health. I’m Sarah Ann Macklin, one of the few women scientists in this space, bringing you evidence-based tools that merge nutrition, mindset, and self-compassion for a new, multidimensional approach to wellness. No quick fixes. No one-size-fits-all solutions. Just real expert-driven science and practical strategies to help you take control of your internal health, not simply external. Join me as I share cutting- ...
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In this clip, we’re with my guest Dr. William Li, a renowned physician, scientist, and author of "Eat to Beat Disease," to discuss the critical topic of Alzheimer's and dementia. We delve into the factors that contribute to cognitive decline and explore actionable strategies for prevention. Dr. Li shares insights on how our gut microbiome profoundl…
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Rethinking relationships: Is friendship the key to happiness? This episode flips the script on traditional views of love and partnership. Our guest argues that we've put romantic relationships on a pedestal, potentially overlooking the profound value of friendships. Key points: Why some friendships outshine romantic partnerships The pressure to fin…
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In this episode, my guest is Dr. Kristin Neff, a pioneering researcher in self-compassion and an associate professor at the University of Texas at Austin. We discuss how cultivating self-compassion can profoundly transform our relationship with food, our bodies, and our overall well-being. We also explore the impact of self-compassion on eating beh…
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In this clip, my guest is Dr. Lisa Feldman Barrett, a renowned neuroscientist and psychologist specializing in the science of emotion. We delve into the fascinating concept of the brain's "body budget"—how our brains predict and regulate the needs of our bodies through a process called allostasis. Lisa explains how disruptions in this body budgetin…
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In this episode, I explore the world of stress with experts Alice Law and Mo Gawdat. We unpack their innovative 'Ton of Stress' model and the TONN framework, revealing why being "busy" is a health risk, not a badge of honor. Alice and Mo share evidence-based strategies to identify stress triggers and build resilience. They explain the surprising ba…
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What happens when you confront your deepest fears? In this inspiring episode, free diver Li Karlsen takes us beneath the ice to share her incredible journey of overcoming fear in one of the planet's most extreme environments. Diving under massive icebergs into freezing, dark waters, Li faced the ultimate challenge—both physically and mentally. Thro…
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In this clip, my guest is Dr. Kanchan Koya, Ph.D., a molecular biologist and health coach who specializes in the health benefits of spices. We discuss the surprising and powerful effects of incorporating culinary amounts of spices into everyday meals. We also explore recent human studies demonstrating how small additions of spice blends can signifi…
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Did you know your diet could be the secret weapon for protecting your brain? In this video, Dr. William Li uncovers how certain foods can fortify one of your brain’s most vital but overlooked defenses – the blood-brain barrier. This essential filter shields your mind from harmful invaders, yet many people don’t realize how everyday foods can help k…
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Be Well Moments brings you my favorite bite-sized highlights from the season. Enjoy quick insights from our longer conversations in a digestible format. If you'd like to listen or watch the full episode, click the link below. Dr. Shefali, a psychologist and author, explains the 'shadow self' - a part of us we often ignore. She shows how this hidden…
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Be Well Moments brings you my favorite bite-sized highlights from the season. Enjoy quick insights from our longer conversations in a digestible format. If you'd like to listen or watch the full episode, click the link below. Dr. Casey Means, a leading voice in metabolic health, unpacks the intricate connection between metabolism and our overall we…
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Be Well Moments brings you my favorite bite-sized highlights from the season. Enjoy quick insights from our longer conversations in a digestible format. If you'd like to listen or watch the full episode, click the link below. Are you doing friendship right? Simon Sinek talks about what it means to be a friend today. He shares an '8-minute rule' tha…
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Many of us think self-compassion is just about being kind to ourselves, or even perhaps that it implies a sense of laziness or self-indulgence. But Dr. Kristin Neff completely challenges these ideas. She reveals how self-compassion is actually a powerful tool for motivation and resilience, and explains why our culture, and even our evolutionary ins…
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Cortisol is synonymous with stress. However, according to Dr. Lisa Feldman Barrett, it isn’t really the ‘stress hormone’ we all think it is. In today’s episode, Dr. Feldman Barrett shares a different view on how the brain handles stress and uncertainty, and that it is always predicting and shaping our reality. She talks about "body budgeting" and h…
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Stress is something we all deal with, but did you know that it affects us in four different ways? Stress can impact us mentally, emotionally, physically, and spiritually, and in this episode we look into all four modalities and how to recognise them. Mo Gawdat is a former Chief Business Officer at Google X and a bestselling author, and Alice Law is…
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Here’s my wonderful conversation with Li Karlsen, a freediver and former Swedish Army captain. She served for 20 years before discovering freediving at 35. Li has broken records, including a 200-metre dive on one breath, and a dive under Greenland's ice. Now she helps others face their fears. We talked about her change from military life to ocean d…
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Dr. William Li is back on Live Well, Be Well! Mental health is a huge focus for me, and with good reason. Dementia's on the rise, and many people can resonate with the brain fog that comes as a consequence of our fast-paced world. But - did you ever think that being picky with food might mess with your mental health? Dr. William Li breaks down this…
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Probiotics are often touted as a staple of gut health, but here Dr. James Kinross discusses the advancement of probiotic science, and how a range of treatments and drugs will shape the future of the microbiome and the gut-brain connection. Listen to the full episode here. Watch the full episode on YouTube here.…
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Spices as medicine? Today I chat with Kanchan Koya, a Harvard-trained molecular biologist who traded the lab for the kitchen, and now runs Spice Spice Baby and has a cookbook packed with vibrant spice-filled recipes. We dig into the science behind spices - from fighting inflammation to boosting gut health. Did you know a dash of cinnamon could help…
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Discover how Hormone Replacement Therapy (HRT) can transform your life at any age with Dr. Louise Newson, a GP and hormone specialist. Sarah Ann shares her own personal experience of working with Dr. Louise and the life-changing effects it has had, so watch now to learn more about how taking hormones may be the missing piece of the puzzle. Listen t…
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Today, I sit down with Sharmadean Reid, a leader in the worlds of beauty, tech, and media. With a 20-year career that includes launching an innovative salon as well as founding a beauty tech startup, Sharmadean has consistently broken barriers. She was the first black woman to raise £1 million in VC funding in the UK and was awarded an MBE in 2015 …
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Creatine is commonly known for its benefits in athletic performance, but did you know it also plays a crucial role in brain health? Dr. Tommy Wood has a ph.D. in physiology and neuroscience, and here he shares the science behind creatine's cognitive benefits, as well as a study that compared the effects of creatine and caffeine in those who are sle…
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Can consciousness transform our lives and relationships? My recent conversation with Dr. Shefali would suggest so. What began as a discussion about self-awareness evolved into a deep exploration of how consciousness can transform every aspect of our lives, from our relationships to our sense of purpose. Dr. Shefali not only offers insights and stra…
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Events don't cause stress, what causes stress are the views you have of those events. We have the power in our minds to control how we respond to events, and ultimately how we respond to everything. Harvard Psychologist Dr. Ellen Langer shares how when we connect the mind and body, we can learn how to reduce stress and see profound health benefits.…
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I'm thrilled to bring you my conversation with Dr. Casey Means, who is an expert in metabolic health. In this episode, we explore the science behind metabolic function and its impact on our overall health and wellbeing. Dr. Casey Means is a Stanford-trained physician and entrepreneur who graduated top of her class from Stanford Medical School. Afte…
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Willpower has long been associated with self-control, but why has it not been associated with the ingredients in our foods? Dr. Chris van Tulleken is one of the BBC’s leading science presenters and author of the groundbreaking book, Ultra-Processed People. He discusses how ultra-processed foods and willpower are so closely linked, and why a seeming…
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