Những podcast Julia Nelson hay nhất (2024)

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EP 160: Artificial Intelligence, GWAS in Drug Discovery, and Career Insights with Dr. Eric Fauman, Executive Director and Head of Computational Biology in the Internal Medicine Research Unit at Pfizer 52:25

4d ago52:25

52:25

0:00 Introduction 1:30 The power of social media: How Eric published 10 papers based on ideas that he discussed on Twitter 5:50 Explanation of The Table of Everything, an internal database at Pfizer that catalogs nearly 20,000 human genes and their associated diseases and traits 13:20 How Eric’s team works to correlate genome-wide association study…

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EP 159: Engineering macrophages to tackle rare disease with Noam Baumatz of Noga Therapeutics 44:17

14d ago44:17

44:17

0:00 Intro to The Genetics Podcast 01:00 Welcome to Noam and discussion of his motivation to drive rare disease forward 03:00 Noam’s daughter Noga’s experience of rare disease, including an 8 to 12 month journey to diagnosis 05:10 How the experience of his daughter receiving a genetic diagnosis motivated Noam to take change into his own hands 10:12…

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#83 - You've Got To Hide Your Love Away with Steven Page 1:18:11

14d ago1:18:11

1:18:11

Thousands of words have been written about Bob Dylan's influence on the Beatles. Despite all those words, one need look no further than "You've Got to Hide Your Love Away" from the Help! album. Taking the folk trademark of heavily strummed 6 and 12 string acoustic and nylon string guitars, minimal instrumentation, the song finds John delivering (up…

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The Pit - with David Simpson 38:53

20d ago38:53

38:53

In this episode, we chat to David Simpson about his career, wherein he gives some terrifying advice to would-be speakers... Face the Wall... in The Pit. Learn more about IDUG, the International Db2 User Group, at www.idug.org.

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EP 158: Research Roundup with Dr Veera: Discoveries in neurogenetics, evolution, cardiac arrhythmias, and more! 1:11:31

8d ago1:11:31

1:11:31

0:00 Invitation to The Genetics Podcast meetup 1:30 Intro to The Genetics Podcast 2:30 Welcome to Veera 3:20 The evolution on skin color in humans and their ancestors: Discussion on how a retrotransposon—often called a "jumping gene"—within the ASIP gene (agouti signaling protein) influenced the evolution of skin pigmentation in humans and their an…

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EP 157: Bridging genomics, business, and equity in healthcare access with Mark Taylor of LGC Group 35:40

28d ago35:40

35:40

0:00 Invitation to The Genetics Podcast meet up 1:30 Intro to The Genetics Podcast 2:25 Welcome to Mark 3:10 Introduction to the National Institute for Health Research (NIHR) 4:05 Mark’s roles with the NIHR in strategic partnerships 7:35 Challenges patients face in accessing NHS resources and the NIHR’s efforts to streamline availability 13:25 How …

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#84 - Old Brown Shoe with guest Sean Nelson 1:48:11

28d ago1:48:11

1:48:11

Upon rejoining the band following his departure in the Get Back sessions, George pulled his more serious material, most of which would end up on All Things Must Pass. Along with his blusey and lightweight "For You Blue," he also brought in a stomping little piano song he wrote during the sessions, "Old Brown Shoe." It wouldn't find a home for a few…

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EP 156: The Genetics Podcast In-Person Event! 1:32

1M ago1:32

1:32

We hope you will join us at our first (of hopefully many!) in-person podcast event! Please use this link to sign up.Bởi Sano Genetics

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EP 155: Adeno-associated virus as a delivery vector for genetic eye disease treatment, with Paul Wille of Abeona Therapeutics 32:18

1M ago32:18

32:18

0:00 Invitation to our first in-person podcast event 1:30 Intro to The Genetics Podcast 2:20 Welcome to Paul 2:53 Adeno-associated virus (AAV) biology and its advantages over other viral vectors 5:20 The gene therapy landscape and options for therapy development and delivery 6:49 The limitations of working with AAV to deliver gene therapy, includin…

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EP 154: Pioneering early disease detection through wearable devices and regular monitoring with Dr. Mike Snyder 41:03

1M ago41:03

41:03

0:00 Introduction 1:00 Overview of Mike’s background and contributions to genomics and preventative medicine, as well as how he first became interested in deep data collection for health monitoring 4:20 The use of various tools, including smartwatches, blood tests, genetic testing, and more, to create a comprehensive view of an individual’s health …

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EP 153: How genomics is re-writing the taxonomy of disease with Lon Cardon, President and CEO of The Jackson Laboratory 40:25

2M ago40:25

40:25

0:00 Intro to The Genetics Podcast 01:00 Welcome to Lon 01:51 Lon’s involvement in the very first GWAS and what drew him to large-scale genomics research 03:32 Was moving away from candidate genes towards GWAS and data sharing initially a controversial idea? 05:25 What Lon believes has driven collaboration and data sharing within research communiti…

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EP 152: Unlocking the secrets of gene regulation with Nadav Ahituv, Director of the Institute of Human Genetics at UCSF 42:40

2M ago42:40

42:40

01:15 - Introductions 02:02 - How our understanding of the non-coding genome has evolved throughout Nadav’s career 04:56 - Our current understanding of non-coding genome grammar 07:40 - Is there a missing piece to the common variant, common disease paradigm? 10:25 - Introducing ultraconserved elements (UCEs) and human accelerated regions (HARs) 12:…

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A chat with IBM Lifetime Champion Dusty Rivers 48:21

2M ago48:21

48:21

It's a privilege to speak with a DB2 expert who has been around since the beginning - literally. Dusty Rivers is a 47-year industry veteran who has his own quantum chip and can explain why it was called Db2 in the first place (at least in theory). He also suggests that if you're new to the Db2 community, you should know who you'd like to meet at co…

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EP 151: Understanding cell ageing and its role in disease with Marco Quarta Co-founder and CEO of Rubedo Life Sciences 42:36

2M ago42:36

42:36

0:00 Intro to The Genetics Podcast 01:00 Welcome to Marco 02:00 The areas Marco focused on during his academic career and what motivated him to found his first company 03:18 How our understanding of ageing has changed over the past two decades and some of the current big questions in ageing biology 06:01 How to get a clearer picture of the ageing p…

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EP 150: Cracking the biological code of aging with Martin Borch Jensen, Co-Founder and Chief Scientific Officer at Gordian Biotechnology 44:21

2M ago44:21

44:21

0:00 Intro to The Genetics Podcast 01:00 Welcome to Martin 01:35 How a particularly large Indian meal resulted in a book about intermittent fasting and the biology of ageing 05:10 The biological mechanisms behind intermittent fasting, and whether it’s been established to extend life expectancy in humans. 10:13 What we know (and what we don’t) about…

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EP 149: Sequencing 33 million samples to support the UK’s COVID-19 response with Tony Cox, CEO of UK Biocentre 34:16

3M ago34:16

34:16

0:00 Intro to The Genetics Podcast 01:00 Welcome to Tony 02:00 What Tony was expecting going into the role of CEO at UK Biocentre, and how the COVID-19 pandemic changed his plans 03:38 Receiving a phone call from the UK government in March 2020 asking the UK Biocentre to stop all of its projects and focus on sequencing COVID-19 samples 05:12 The UK…

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Spoilers! with Miran Badzak 49:04

3M ago49:04

49:04

What do a long line at the DMV, a packet of chewing gum, and your bank balance have in common? Miran Badzak explains while reflecting on Db2's best year on record (2023). He also teases some new product announcements that will be shared at IDUG's 2024 EMEA Db2 Tech Conference this fall. (Think AI optimization, performance and UX improvements, and d…

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EP 148: Advancing veteran health through the Million Veteran Program with Dr. Mike Gaziano, professor of medicine at Harvard Medical School 35:13

3M ago35:13

35:13

0:00 Intro 2:00 Mike’s career prior to the Million Veteran Program (MVP), how Mike got to work on MVP, and important milestones in the project's evolution 8:30 Future goals for the Million Veteran Program in expanding and diversifying the research cohort 11:00 The roles of various omics in advancing the project's development 14:30 The most meaningf…

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EP 147: From research to delivering precision medicine in the clinic with Scott Weiss, Professor of Medicine at Harvard University 37:19

3M ago37:19

37:19

0:00 Intro to The Genetics Podcast 01:00 Welcome to Scott 01:55 Scott’s career highlights to date, ranging from epidemiology to the genetics of asthma and chronic obstructive pulmonary disease (COPD) 04:56 How and why Scott decided to transition into genetics 06:30 The advances in our understanding of the genetics of asthma and COPD over the past 2…

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EP 146: The biology of aging with Austin Argentieri, Research Fellow at Harvard Medical School, Affiliate Member of the Broad Institute, and Research Fellow at Massachusetts General Hospital 43:05

3M ago43:05

43:05

0:00 Intro to The Genetics Podcast 01:00 Welcome to Austin 01:42 What is aging and how should we think about it? 03:50 Discussion of Austin’s recent breakthrough paper on aging, including the questions he set out to answer, and the outcomes of the research 06:32 How Austin’s work focuses on using large-scale population proteomics data to create acc…

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EP 145: Navigating rare disease drug development regulations with Daniel O’Connor 39:12

4M ago39:12

39:12

0:00 Intro to The Genetics Podcast 01:00 Welcome to Daniel 02:04 Defining rare disease in the age of personalized medicine 04:57 Key touchpoints with the Medicines and Healthcare products Regulatory Agency (MHRA) when developing a new medicine 09:27 Improvements over the course of Daniel’s career when it comes to incentivizing and making the path t…

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EP 144: Research Roundup with Dr. Veera: breakthroughs in developmental disorders, Parkinson's, SLE, and Alzheimer's 56:48

4M ago56:48

56:48

0:00 Introduction 1:40 A recurrent de novo mutation in a noncoding region of a small nucleolar RNA gene that has been identified as one of the most common causes of neurodevelopmental disorders This pathogenic variant escaped notice for years because it was not located in a protein coding region of the genome It now shows potential as a target for …

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#85 - One After 909 with BC The Beatles 1:17:21

4M ago1:17:21

1:17:21

As a songwriter, I could never imagine at this point in my life, putting out song a wrote at 16 or 17. I don't ever want anyone to hear that. But then again, I'm not the Beatles, who were able to resurrect one of the earliest songs in their repertoire, from well before they were even The Beatles. Though the song was in their early setlists for a lo…

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EP 143: Harnessing human data in drug development with Jakob Steinfeldt, Co-Founder and Chief Scientific Officer at Pheiron 36:17

4M ago36:17

36:17

0:00 Intro to The Genetics Podcast 01:00 Welcome to Jakob and background on Pheiron 02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up 5:24 Jakob’s excitement and inspiration around the power and potential of machine learning 07:07 Cardiology and heart failure as …

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Found: Experienced Db2 Game Show Hosts with Victoria Felt and Keziah Knopp 43:04

4M ago43:04

43:04

This dynamic duo already has a cult following for their presentations, and they've breathed fresh air into our typically dusty, gray-haired podcast this month. Victoria Felt and Keziah Knopp are new enough in their careers that nothing really embarrassing has happened yet, but we do delve into some other interesting areas including broken bones and…

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#86 - Baby's In Black with Andy Nicholes (co-host 2Legs Podcast) 1:16:06

4M ago1:16:06

1:16:06

Though the Lennon & McCartney songwriting team found it harder and harder to truly write songs together from scratch as they got busier and busier, with "Baby's In Black," they were able to get "nose-to-nose" and write something truly different from what was expected at the time. A 3/4 time waltz with a melancholy lyric (possibly inspired by Astrid…

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EP 142: From genome to bedside: How genetics is transforming modern medical practice with Dr. Andrea Gropman 42:45

4M ago42:45

42:45

0:00 Introduction 1:40 Andrea’s background and how she got into the field of genetics, neuroimaging, and metabolic disorders 4:00 Insights into Andrea’s clinical practice, including the diverse families and patients she serves and her approach to clinical decision-making 6:30 How genetics and genomics have changed the diagnostic journey in the last…

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EP 141: Bringing genomics to the clinic with Lori Orlando, Associate Prof at Duke University 43:24

4M ago43:24

43:24

0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…

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#87 - You Never Give Me Your Money with Tom Hunyady (co-host, 2Legs and Talk More Talk podcasts) 1:29:29

5M ago1:29:29

1:29:29

In many ways, Paul McCartney is the ultimate storyteller. He's got an unparalleled ability to craft characters and a situations that are so vivid, you can't easily tell when he's hiding his own feelings and life stories in them. So when we writes a song where he's totally upfront about a situation, no story, no characters, you can bet it's somethin…

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EP 140: The future of Electronic Health Records and data analysis with Ben Goldacre 52:51

5M ago52:51

52:51

0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…

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#88 - No Reply with guest Jeff Slate (musician, journalist) 1:25:58

5M ago1:25:58

1:25:58

The journey of "No Reply" is a curious one. A song John seemed to not think much of, and originally offered to another Brian Epstein-managed artist, it also was possibly slated to be the final song recorded for A Hard Day's Night. If not for Ringo's tonsillitis, who knows what would've happened with it. After spending some time with it though, and …

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EP 139: Rare disease breakthroughs using tRNA with Michelle Werner, CEO of Alltrna and CEO-Partner of Flagship Pioneering 44:42

5M ago44:42

44:42

0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…

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#89 - Lady Madonna with Davis Rogan (pianist, host DJ Davis' Tasting Notes)) 1:10:41

5M ago1:10:41

1:10:41

After spending a year and half out firmly planted in psychedelia, The Beatles returned to Earth at the beginning of 1968 with "Lady Madonna," a Paul-penned tune that pays tribute to the strength of women, a topic he mines throughout his career. The song also serves an homage to New Orleans' piano legend and rock and roll trail blazer Fats Domino, a…

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'The greatest man I ever knew' — Andrew Moran's eulogy for father Lawrence Moran, Melbourne 2023 54:38

5M ago54:38

54:38

Since 2006, Andrew Moran has been a baritone with Opera Australia in Sydney. When he visited Melbourne as part of a touring production of Puccini's Tosca, Tony spoke to him about a lovely eulogy he delivered for his father, Lawrie Moran, the man who inspired him to sing, in Surrey Hills, Melbourne, on 9 November 2023. You can read and listen to the…

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EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken 40:22

5M ago40:22

40:22

0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…

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Not-Exactly-Tech Talk with George Baklarz 50:42

5M ago50:42

50:42

Generally acknowledged as a Big Star in the world of LUW, George Baklarz discusses his history with IBM and the Db2 community, and shares his thoughts on how to be a bridge between the technical community and its customers and end-users. Learn more about IDUG, the International Db2 User Group, at www.idug.org.…

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EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research 41:40

6M ago41:40

41:40

0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…

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#90 - The Inner Light with Caitlin Larkin (DJ, Sirius XM The Beatles Channel) 1:19:16

6M ago1:19:16

1:19:16

There seems to be somewhat of a misconception of The Beatles having a really big "Indian period." In reality, there's only 3 songs that really fit that bill, and the 3rd a final one, "The Inner Light," may be the most open hearted and enlightened one. After being inspired/challenged by a scholar he met on the David Frost show, George took lyrics fr…

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#91 - Everybody's Got Something To Hide Except Me and My Monkey with guest Brian Marchese (host, Where's That Sound Coming From?) 1:47:57

6M ago1:47:57

1:47:57

The longest titled song in the Beatles' catalogue is also one that maybe flies a bit below the radar. Buried on side 3 of the White album, "Everybody's Got Something To Hide Except Me and My Monkey" is one of the heaviest rockers in the back half of their career. Inspired by the Maharishi, and also possibly by a growing drug issue, John leads the b…

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EP 136: Developments in ring chromosome 20 research and advocacy with Allison Watson 40:57

6M ago40:57

40:57

0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…

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A Lloyds Reunion and more with Phil Nelson 51:16

6M ago51:16

51:16

Long-time IDUG supporter Phil Nelson never meant to be an IT guy at all...and if he'd known his first IDUG abstract would be accepted, he may never have submitted it. (Presented on foils, no less.) Learn more about IDUG, the International Db2 User Group, at www.idug.org.Bởi Julia Carter & Marcus Davage for IDUG

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EP 135: Integration of newborn sequencing programs into healthcare systems with Dr. Ingrid Holm 41:16

6M ago41:16

41:16

0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…

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BONUS! A Let It Be Podcast Roundtable Chat 1:53:58

6M ago1:53:58

1:53:58

After decades of hiding in the Apple vaults, the Beatles' 1970 film Let It Be is finally out! Lovingly restored thanks to Peter Jackson's team, the documentary directed by Michael Lindsay-Hogg finally gets it place in the sun. What better way to celebrate than with Beatle pals!?!? We were thrilled as could be to join our pals from the Blotto Beatle…

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EP 134: Prenatal genetic testing and the future of AI in genetic counselling with Kira Dineen, host of DNA Today 40:44

6M ago40:44

40:44

0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…

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#92 - If I Needed Someone with Ethan Alexanian (host, Fans on the Run) 1:13:53

6M ago1:13:53

1:13:53

Imagine the feeling you'd get when the band that was the inspiration for YOUR band put out a song and told everyone YOUR band inspired that song? Probably a pretty amazing feeling. That's exactly what happened when The Beatles released the George Harrison-penned "If I Needed Someone" on Rubber Soul in December 1965. George was quick to give credit …

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EP 133: Insights into pharmacogenomics and increasing diversity in genomics research with Dr. Emma Magavern 39:17

7M ago39:17

39:17

0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…

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#93 - Honey Pie with Dr. Christine Feldman-Barrett, author (A Women's History of the Beatles, The Life, Death, and Afterlife of the Record Store) 1:09:54

7M ago1:09:54

1:09:54

Much has been discussed of Paul McCartney's love of what John Lennon called "granny music." The music of his parents' generation, British Music Hall, Vaudeville, Tin Pan Alley...you know the genre...the stuff Lennon loved to complain about when it came from Paul, but seemingly had no problem with his favorite group, Nilsson, whos stock and trade wa…

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EP 132: From mammoths to genome editing, trailblazing genetics with Dr. George Church 47:41

7M ago47:41

47:41

0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…

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#94 - Free As A Bird with Skylar Moody (Beatles content creator, journalist) 1:24:43

7M ago1:24:43

1:24:43

Some 25 years after the Beatles' break up, new music from the band emerged via a cosmic combination of technology and enduring love...and the career-spanning Anthology project. Using a solo John piano demo, the remaining Threetles completed "Free As A Bird," a stately and beautiful track, complete with the still gorgeous Beatle harmony, brilliant l…

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EP 131: The potential of somatic genomics in drug discovery and development with Jake Rubens 44:57

7M ago44:57

44:57

0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…

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