Ep #77: Hormone Replacement Therapy (HRT) Risk & Benefits with Dr. JoAnn Manson

Menopause Reimagined with Andrea Donsky

Join Andrea Donsky, nutritionist, Menopause Educator, Menopause researcher, and Co-founder of wearemorphus.com, and Dr. JoAnn Manson as they re-examine the results of the Women's Health Initiative Study.
Timestamps:
0:21 Andrea outlines the many accomplishments of Dr. JoAnn Manson.
2:18 Andrea and Dr. Manson discuss how the WHI Study focused on post-menopausal women's health and the purpose of the three trials. Two trials focused on hormone therapy and preventing chronic diseases such as heart attacks, strokes, cognitive decline, and related outcomes not the effectiveness of hormone therapy. Another study focused on calcium and vitamin D and the relationship to reducing fractures. The third study was the low-fat diet and whether it correlated to lower breast and colorectal cancer incidences.
7:47 How the results of one of the studies became the focus and controversial.
13:45 Discussing how hormone therapy has evolved and changed since the study 20 years ago.
18:51 Information on how the medical education system short-changes women in perimenopause and menopause.
23:50 The importance of behavioral and lifestyle changes that can be made to improve long-term health outcomes that was studied in the Nurse's Health Study.
26:05 Hormone therapy and the nuances of the findings of therapy in early menopause vs. studying women in their 60s, 70s, and 80s.
30:14 The current thinking about the best candidates for hormone therapy.
34:05 If Dr. Manson could redo the WHI study what would she do differently?
39:46 Next steps women can take in finding a practitioner.
JoAnn E. Manson, MD, MPH, DrPH, MACP, is a Professor of Medicine and the Michael and Lee Bell Professor of Women’s Health at Harvard Medical School, Professor in the Department of Epidemiology, Harvard T.H. Chan School of Public Health, and Chief of the Division of Preventive Medicine at Brigham and Women's Hospital (BWH). Dr. Manson is a physician epidemiologist, endocrinologist, and Principal Investigator (PI) or co-PI of several research studies, including the Women’s Health Initiative Clinical Center In Boston, the cardiovascular component of the Nurses’ Health Study, the VITamin D and OmegA-3 TriaL (VITAL) and the COSMOS trial.
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