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Freely Filtered 058: HCTZ v Chlorthalidone, The Diuretic Comparison Project
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Manage episode 362194390 series 2540759
The Filtrate:
Joel Topf
Swapnil Hiremath
Josh Waitzman
Jordy Cohen
With Special Guest:
Areef ishani lead author and Chief of Medicine VA Minneapolis
Editor:
Nayan Arora
Show Notes:
MRFIT switches diuretics and finds better outcomes.
Swapnil shows how many studies he is familiar with by spewing out a string of them.
Chlorthalidone wins: ALLHAT, MRFIT, SPRINT, HYVET, CLICK (not mentioned by Swap but by Jordy later)
HCTZ loses: HOPE3, ACCOMPLISH
Diuretic half-lifes NEJM review
Edarbyclor: Azilsartan and Chlorthalidone $240/month as per GoodRx
Nice mention of late study originator Frank Lederle. Please see his article in Annals about his diagnosis of pancreatic cancer. Moving.
Network analysis of HCTZ vs chlorthalidone
Antihypertensive efficacy of hydrochlorothiazide vs chlorthalidone combined with azilsartan medoxomil by George Bakris
Synopsis of the 2020 U.S. Department of Veterans Affairs/U.S. Department of Defense Clinical Practice Guideline: The Diagnosis and Management of Hypertension in the Primary Care Setting (Annals of Internal Medicine)
Testing for Primary Aldosteronism and Mineralocorticoid Receptor Antagonist Use Among U.S. Veterans: A Retrospective Cohort Study by Jordy Cohen
Study showing better risk reward ratio of low dose than high dose thiazide diuretics. Treatment of hypertension in the elderly: I. Blood pressure and clinical changes. Results of a Department of Veterans Affairs Cooperative Study.
Tubular Secretions
Swapnil Louise Penny author of book upon which the Amazon Prime series, Three Pines is based on.
Jordy Last of Us series on HBO
Josh Channel Your Enthusiasm A Very Special Episode: Meet the Glaucomfleckens
Areef The Body: A Guide for Occupants
Joel NephMadness (this did not age well)
73 tập
Fetch error
Hmmm there seems to be a problem fetching this series right now. Last successful fetch was on August 01, 2024 14:40 ()
What now? This series will be checked again in the next day. If you believe it should be working, please verify the publisher's feed link below is valid and includes actual episode links. You can contact support to request the feed be immediately fetched.
Manage episode 362194390 series 2540759
The Filtrate:
Joel Topf
Swapnil Hiremath
Josh Waitzman
Jordy Cohen
With Special Guest:
Areef ishani lead author and Chief of Medicine VA Minneapolis
Editor:
Nayan Arora
Show Notes:
MRFIT switches diuretics and finds better outcomes.
Swapnil shows how many studies he is familiar with by spewing out a string of them.
Chlorthalidone wins: ALLHAT, MRFIT, SPRINT, HYVET, CLICK (not mentioned by Swap but by Jordy later)
HCTZ loses: HOPE3, ACCOMPLISH
Diuretic half-lifes NEJM review
Edarbyclor: Azilsartan and Chlorthalidone $240/month as per GoodRx
Nice mention of late study originator Frank Lederle. Please see his article in Annals about his diagnosis of pancreatic cancer. Moving.
Network analysis of HCTZ vs chlorthalidone
Antihypertensive efficacy of hydrochlorothiazide vs chlorthalidone combined with azilsartan medoxomil by George Bakris
Synopsis of the 2020 U.S. Department of Veterans Affairs/U.S. Department of Defense Clinical Practice Guideline: The Diagnosis and Management of Hypertension in the Primary Care Setting (Annals of Internal Medicine)
Testing for Primary Aldosteronism and Mineralocorticoid Receptor Antagonist Use Among U.S. Veterans: A Retrospective Cohort Study by Jordy Cohen
Study showing better risk reward ratio of low dose than high dose thiazide diuretics. Treatment of hypertension in the elderly: I. Blood pressure and clinical changes. Results of a Department of Veterans Affairs Cooperative Study.
Tubular Secretions
Swapnil Louise Penny author of book upon which the Amazon Prime series, Three Pines is based on.
Jordy Last of Us series on HBO
Josh Channel Your Enthusiasm A Very Special Episode: Meet the Glaucomfleckens
Areef The Body: A Guide for Occupants
Joel NephMadness (this did not age well)
73 tập
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