Think You're a GLP-1 Non-Responder? Address These Key Issues First

The Obesity Guide with Matthea Rentea MD

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Are you frustrated because your GLP-1 medication isn’t delivering the rapid results other people seem to achieve? It’s common to feel disappointed when your progress falls short of expectations. I know all too well the desire for that “magic” solution where all the challenges of obesity disappear overnight and you can achieve your goals effortlessly. Unfortunately, that’s not the reality for most people.

In this episode, I’ll dive into why some people experience slower results than others and clarify why terms like "non-responders" or "hypo-responders" might not be helpful if you haven't first addressed key lifestyle factors like hydration, protein intake, and sleep. Join me as I break down the numbers for successful weight loss with GLP-1 medications, share real-life insights into medication effectiveness, and offer practical advice on how to make the most out of your GLP-1 medication.
References
The Top 5 Mistakes That People Make When Starting a GLP-1
Ep. 69 - BMI: Proof it Falls Short as a Measure of Health
My Doctor Started Me on a GLP-1: Now What? Spotify Playlist
Audio Stamps
01:44 - Patients often feel frustrated with slow responses to anti-obesity medications because they aren't given clear expectations at the start.
04:00 - When starting GLP-1 medications, aiming for a 5% weight loss in 12 weeks ensures continued insurance coverage and effective results.
08:28 - Dr. Rentea shares the maximum percentage of total body weight to lose per week when starting GLP-1 medications like Wegovy or Ozempic.
10:45 - If you're not losing at least 5% of your body weight in the first 12 weeks on GLP-1 medications, Dr. Rentea advises you to evaluate key areas of your lifestyle and habits to improve results.
14:13 - Dr. Rentea shares an example of how convenient options can help maintain nutritional goals.

Quotes
“A lot of people think that they're going to start and it's just like fireworks and everything's going to be amazing.” - Matthea Rentea MD
“From a weight loss standpoint, on average we're going to look for at least 5 percent total body weight reduction within the first 12 weeks.” - Matthea Rentea MD
“The max percentage that we want you to lose total body weight per week would be 1%.” - Matthea Rentea MD
“We don't need to wait for week 12 to know that there's an alarm going.” - Matthea Rentea MD
“We cannot say that you're a hypo-responder if you're having a bunch of processed food, if you're not hydrating, if you're not moving, if you're not taking your sleep seriously. These things matter.” - Matthea Rentea MD

All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.
If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com