#188 - Dr. Marc Milstein: The Age-Proof Brain, Amyloid Plaques & Brain Trash, The Glymphatic System, Dementia & Alzheimer's Disease, APOE Gene Risk Factor, Memory Building, Diet For Brain Health, And More!

The Melanie Avalon Biohacking Podcast

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/ageproofbrain

2:35 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!

2:45 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon

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6:05 - FOOD SENSE GUIDE: Get Melanie's App At Melanieavalon.com/foodsenseguide To Tackle Your Food Sensitivities! Food Sense Includes A Searchable Catalogue Of 300+ Foods, Revealing Their Gluten, FODMAP, Lectin, Histamine, Amine, Glutamate, Oxalate, Salicylate, Sulfite, And Thiol Status. Food Sense Also Includes Compound Overviews, Reactions To Look For, Lists Of Foods High And Low In Them, The Ability To Create Your Own Personal Lists, And More!

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11:30 - Marc's Background

13:30 - Insulin Degrading Enzyme

14:50 - The Relationship Between Insulin Levels And Brain Health

16:05 - The Problem With 2 New Alzheimer's Medications

18:30 - Defining The Brain Plaques And The Relation To Cognitive Decline

20:30 - Can You Have Cognitive Decline Without Brain Waste?

21:40 - Diagnosing Brain Waste

22:40 - How To Get Rid Of Brian Waste

26:10 - The Glymphatic System

28:00 - How Is The Waste Removed

29:00 - What Is The Role Of Brain Fluid?

30:10 - Is There A Relation To Intelligence?

31:15 - The Size Of Our Brain And How It Changes

34:45 - What Is Active Learning?

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42:00 - Is Pruning More Genetic Or Environmental

43:25 - How Much Influence Do Parental Rearing Have On Brain Development?

47:30 - How We Crystalize Memories By Revisiting Them

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51:00 - Why Is APOE Connected To Cognitive Decline?

52:50 - Why Did APOE Develop?

53:40 - APOE Risk Factors

55:15 - Memory Formation

58:55 - Short Term Memory

59:30 - Working Memory

1:01:00 - Can We Lose Memories?

1:02:40 - Is Scent The Strongest Recall Of Memory?

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1:07:45 - Distractions And Focus Shift

1:10:15 - The Connection Between Vision Loss Or Hearing Loss And Dementia

1:12:05 - What About Being Born Blind Or Deaf

1:12:50 - Ways To Learn And Ways To Innovate

1:16:45 - The Diet For Brain Health