26: The Insulin Resistance Diabetes Connection

Type 2 Diabetes Talk

Insulin resistance, a condition characterized by the body's impaired ability to respond to the hormone insulin, is at the heart of prediabetes and type 2 diabetes (and many other related health problems too).
In this episode we delve into the complexities of insulin resistance, offering insights into how inflammation plays a pivotal role in its development. We explore the critical role of insulin in regulating blood sugar and how hyperglycemia and hyperinsulinemia can lead to a relentless cycle of metabolic chaos. We dive deep to the core and reveal that the hypothalamus and its nutrient sensors play a significant role in the development of insulin resistance.
We also debunk the popular belief that dietary saturated fat is the primary contributor to insulin resistance, focusing on the abundance of evidence that shows the liver's internal production of palmitic acid (a saturated fat) comes from excess dietary glucose (carbohydrate); and this is the significant driver of diet-induced insulin resistance.
CHAPTERS
2:22 The role of insulin
4:35 Insulin resistance defined
5:40 The liver and insulin resistance
8:21 Effects of insulin resistance throughout the body
14:56 Cause of insulin resistance
17:17 How carbohydrates create saturated fat
22:57 You can change it all!

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Chương

1. 26: The Insulin Resistance Diabetes Connection (00:00:00)

2. The role of insulin (00:02:22)

3. Insulin resistance defined (00:04:35)

4. The liver and insulin resistance (00:05:40)

5. Effects of insulin resistance throughout the body (00:08:21)

6. Cause of insulin resistance (00:14:56)

7. How carbohydrates create saturated fat (00:17:17)

8. You can change it all! (00:22:57)