Novel Antiviral Targets Viral Methyltransferases

Heliox: Where Evidence Meets Empathy

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In this engaging episode of the Deep Dive, two passionate science enthusiasts explore groundbreaking research into a new class of antiviral drugs that target viral methyltransferases. Moving beyond familiar treatments like Paxlovid, they discuss how these novel antivirals could potentially combat a wide range of viruses, from COVID-19 to Ebola and dengue. The hosts break down complex concepts with warmth and clarity, explaining how viruses use methyltransferases as a "disguise" to evade our immune system and how targeting these enzymes could revolutionize our approach to treating viral infections. They thoughtfully explore not just the science, but also the broader implications for global health, pandemic preparedness, and the future of medicine. Join them for an illuminating conversation that makes cutting-edge research accessible while capturing the excitement and promise of this potential medical breakthrough.

Small-molecule inhibition of SARS-CoV-2 NSP14 RNA cap methyltransferase
https://www.nature.com/articles/s41586-024-08320-0

A Novel Class of Antivirals Targets Enzymes Common to Many RNA Viruses
https://www.technologynetworks.com/biopharma/news/a-novel-class-of-antivirals-targets-enzymes-common-to-many-rna-viruses-394223

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